Cetylpyridinium Chloride (CPC)

INCI: CETYLPYRIDINIUM CHLORIDE

Cetylpyridinium Chloride (CPC) (CAS None) is a cosmetic preservative functioning as Preservative. EU Regulation 1223/2009 status: permitted, max 0.1%. Industrial safety data is also available in the chemical safety database.

View industrial chemical safety profile for CAS None →

Auto-generated CPSR Part A draft with source citations
Function
Preservative
Safety Rating
GOOD

Regulatory Status

EU EU Status permitted
EU Max Conc. 0.1%
US US Status permitted
US Notes No specific restrictions

For full compliance data across multiple jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety, dermal absorption, and sensitization profile summaries for Cetylpyridinium Chloride (CPC).

Calculate MoS for your specific formulation with the MoS Calculator.

Additional Ingredient Properties

1 property record from structured ingredient metadata.

preservative
{"preservative_class": "Quaternary ammonium", "antimicrobial_spectrum_bacteria_gp": "Excellent", "antimicrobial_spectrum_bacteria_gn": "Good", "antimicrobial_spectrum_yeast": "Moderate", "antimicrobial_spectrum_mold": "Weak", "mic_staph_aureus_ppm": "50", "mic_e_coli_ppm": "60", "mic_pseudomonas_ppm": "70", "mic_candida_albicans_ppm": "200", "mic_aspergillus_niger_ppm": "600", "challenge_test_pass…

Expert Verdict

Expert safety assessment and concern-level summary for Cetylpyridinium Chloride (CPC).

Regulatory Flags

SCCS Review

NOAEL Studies Summary

View details ->

Public NOAEL study rows linked to Cetylpyridinium Chloride (CPC) by CAS number or substance name.

Studies
8
Lowest NOAEL
5 mg/kg bw/day
Highest NOAEL
12 mg/kg bw/day
ToxValDB_ECHA_IUCLID ECHA_REACH_reach_study_results_dossiers_23-05-2023.zip

Frequently Asked Questions

Is Cetylpyridinium Chloride (CPC) safe in cosmetics?

Cetylpyridinium Chloride (CPC) has a safety rating of "GOOD" in our database. EU status: permitted. US status: permitted.

Is Cetylpyridinium Chloride (CPC) allowed in the EU?

Cetylpyridinium Chloride (CPC) EU regulatory status: permitted. Maximum allowed concentration: 0.1%. This is based on EU Regulation 1223/2009 and its amendments.

What does Cetylpyridinium Chloride (CPC) do in cosmetics?

Cetylpyridinium Chloride (CPC) functions as: Preservative. It is classified as a Preservative in our database. CAS number: None.

Related Ingredients

4-Hydroxybenzoic Acid
Excellent Same category
Preservative, pH Balancer
Caprylhydroxamic Acid
Excellent Same category
preservative booster, chelating agent
Glyceryl Caprylate
Excellent Same category
Antimicrobial agent; emollient; prese...
Levulinic Acid
Excellent Same category
Preservative (combination systems); a...
Potassium Sorbate
Excellent Same category
preservative
Sodium Benzoate
Excellent Same category
preservative
(AGARICUS BLAZEI FERMENT + GANODERMA LUCIDUM FERMENT + GANODERMA MULTIPILEUM FERMENT) EXTRACT
Good Similar safety
Anti-sebum, Antioxidant, Skin Protecting
(ANGELICA ACUTILOBA/PAEONIA LACTIFLORA/REHMANNIA GLUTINOSA) ROOT/CNIDIUM OFFICINALE RHIZOME EXTRACT
Good Similar safety
Skin Conditioning, Skin Conditioning ...
(ANGELICA ACUTILOBA/PAEONIA LACTIFLORA/REHMANNIA GLUTINOSA/SCUTELLARIA BAICALENSIS) ROOT/(CNIDIUM OFFICINALE/COPTIS CHINENSIS) RHIZOME/GARDENIA JASMINOIDES FRUIT/PHELLODENDRON CHINENSE BARK EXTRACT
Good Similar safety
(ANGELICA GIGAS/GLYCYRRHIZA URALENSIS/REHMANNIA GLUTINOSA ROOT)/ANGELICA GIGAS STEM/CARTHAMUS TINCTORIUS FLOWER/(CARTHAMUS TINCTORIUS/PRUNUS PERSICA SEED)PORIA COCOS WATER
Good Similar safety
Humectant, Skin Conditioning, Skin Pr...
(ANGELICA KEISKEI/CHRYSANTHEMUM ZAWADSKII) LEAF/STEM/CINNAMOMUM CASSIA BARK/TRICHOSANTES KIRILOWII FRUIT/ULMUS DAVIDIANA BARK/ROOT/(PAEONIA JAPONICA/BUPLEURUM FALCATUM/POLYGALA TENUIFOLIA ROOT)/VISCUS ALBUM STEM EXTRACT
Good Similar safety
Anti-seborrheic, Anti-sebum, Antioxid...
(APPLE/CITRUS JUNOS/LENTIL/PEAR/PUMPKIN/STRAWBERRY/TOMATO FRUIT)/CORN KERNEL/(ARCTIUM LAPPA/BRASSICA OLERACEA ACEPHALA/CABBAGE/CAMELLIA SINENSIS/MORINGA OLEIFERA/RADISH/SPINACH LEAF)/(SORGHUM BICOLOR LEAF/STEM)/OAT MEAL/POTATO PULP/(CARROT/NELUMBO NUCIFERA/RADISH/WILD YAM ROOT)/(AMARANTHUS HYPOCHONDRIACUS/CASHEW/CICER ARIETINUM/COIX LACRYMA-JOBI MA-YUEN /MACADAMIA TERNIFOLIA/PHASEOLUS ANGULARIS/PISTACIA VERA/RHYNCHOSIA NULUBILIS/RICE/SESAME/SETARIA ITALICA/SOYBEAN/SWEET ALMOND/WHEAT SEED)/HORDEUM VULGARE SPROUT/CYPERUS ESCULENTUS TUBER/ARTEMISIA PRINCEPS/BROCCOLI/CHENOPODIUM QUINOA/ENTEROMORPHA COMPRESSA/HORDEUM VULGARE/IPOMOEA BATATAS/LAMINARIA JAPONICA/LENTINUS EDODES/PLEUROTUS OSTREATUS/PORPHYRA TENERA/UNDARIA PINNATIFIDA EXTRACT
Good Similar safety
Antioxidant
CETETH-10
Good Browse nearby
Surfactant - Cleansing, Surfactant - ...
CETETH-2
Good Browse nearby
Surfactant - Emulsifying
CETRARIA ISLANDICA THALLUS/POLYPODIUM VULGARE RHIZOME/SPHAGNUM MAGELLANICUM EXTRACT
Good Browse nearby
Humectant, Skin Conditioning

Is Cetylpyridinium Chloride (CPC) in Your Products?

Scan any product label with Piro — our free ingredient scanner. Point your camera at the ingredients list and get instant safety scores for every ingredient.

Try Piro Free →

Analyze Your Full Ingredient List

Paste any INCI list into the Decoder for instant safety analysis, or calculate the Margin of Safety for Cetylpyridinium Chloride (CPC) in your formulation.