Poor Fragrance Sensitization Data

Chloroatranol

INCI: CHLOROATRANOL

CAS Number
57074-21-2
Function
Fragrance
Safety Rating
POOR

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status prohibited
EU Max Conc. 0%
๐Ÿ‡บ๐Ÿ‡ธ US Status permitted
US Notes No federal ban; voluntarily avoided by major brands; indirect exposure via oakmoss and treemoss extracts

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
not established
Dermal Absorption
high
Sensitization
high

Calculate MoS for your specific formulation with the MoS Calculator.

Sensitization Profile

Contact sensitization data for Chloroatranol based on clinical patch test studies and IFRA standards.

Sensitization Rate
low
Allergen Class
fragrance
EU Allergen Listed
yes
Patch Test Positive Rate
0.2%
Cross-reactivity Group
none
Reaction Type
contact-dermatitis
IFRA Restricted

Source: EU 2023/1545; SCCS

Expert Verdict

EU-prohibited at any detectable concentration via Regulation 2017/1410. Severe contact allergen restricted alongside atranol. IFRA sets 100 ppm combined limit in moss extracts to achieve tolerable <0.5 ppm in final fragrance products. Oakmoss and treemoss are the only significant sources of consumer exposure. Do not use as a standalone ingredient.

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Concern Level: High

Regulatory Flags

eu-banned annex-ii contact-allergen eu-2017-1410 natural-origin oakmoss-constituent eu_banned_cosmetics eu_cosing_listed

Frequently Asked Questions

Is Chloroatranol safe in cosmetics?

EU-prohibited at any detectable concentration via Regulation 2017/1410. Severe contact allergen restricted alongside atranol. IFRA sets 100 ppm combined limit in moss extracts to achieve tolerable <0.5 ppm in final fragrance products. Oakmoss and treemoss are the only significant sources of consumer exposure. Do not use as a standalone ingredient. The EU classifies Chloroatranol as "prohibited". Safety rating: POOR.

Is Chloroatranol allowed in the EU?

Chloroatranol EU regulatory status: prohibited. Maximum allowed concentration: 0%. This is based on EU Regulation 1223/2009 and its amendments.

What does Chloroatranol do in cosmetics?

Chloroatranol functions as: Fragrance. It is classified as a Fragrance in our database. CAS number: 57074-21-2.

What is the Margin of Safety for Chloroatranol?

not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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