Choleth-24

INCI: CHOLETH-24

CAS Number
27321-96-6 (generic); specific CAS varies by supplier
Function
Surfactant; emulsifier; solubilizer. PEG-24 ether of cholesterol — most extensively studied of the Choleth series
Safety Rating
MODERATE

Regulatory Status

🇪🇺 EU Status permitted
🇺🇸 US Status permitted
US Notes FDA permitted; also an inactive ingredient in 2 FDA-approved drug formulations. CIR: safe for topical application in present practices of use (1982, reaffirmed 2005, reaffirmed 2022)

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
adequate
Dermal Absorption
low
Sensitization
none

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

Choleth-24 is a PEG-24 ether of cholesterol approved as a surfactant and emulsifier in cosmetic formulations with adequate margin of safety.

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Concern Level: Moderate

Frequently Asked Questions

Is Choleth-24 safe in cosmetics?

Choleth-24 is a PEG-24 ether of cholesterol approved as a surfactant and emulsifier in cosmetic formulations with adequate margin of safety. The EU classifies Choleth-24 as "permitted". Safety rating: MODERATE.

Is Choleth-24 allowed in the EU?

Choleth-24 EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Choleth-24 do in cosmetics?

Choleth-24 functions as: Surfactant; emulsifier; solubilizer. PEG-24 ether of cholesterol — most extensively studied of the Choleth series. It is classified as a cosmetic ingredient in our database. CAS number: 27321-96-6 (generic); specific CAS varies by supplier.

What is the Margin of Safety for Choleth-24?

adequate The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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