CI 77163
Regulatory Status
For full compliance data across 55 jurisdictions, use the Substance Compliance tool.
Safety Data
Calculate MoS for your specific formulation with the MoS Calculator.
Toxicological Studies
6 study endpoints found for CI 77163. NOAEL (No Observed Adverse Effect Level) values are used to calculate the Margin of Safety per SCCS methodology.
| Endpoint | Value | Route | Species | Study Type | Source |
|---|---|---|---|---|---|
| NOAEL | 500 mg/kg bw/day | dermal | code:3484 | dermal | REACH |
| NOAEL | 1000 mg/kg bw/day | oral | rat | oral | REACH |
| NOAEL | 5000 mg/kg bw/day | oral | rat | oral | REACH |
| NOAEL | 500 mg/kg bw/day | dermal | code:3484 | dermal | REACH |
| NOAEL | 500 mg/kg bw/day | dermal | code:3484 | dermal | REACH |
| NOAEL | 1000 mg/kg bw/day | oral | - | oral | REACH |
Expert Verdict
Bismuth oxychloride is a permitted colorant with negligible systemic absorption, though sensitization potential exists; skin irritation and tingling sensations may occur in sensitive individuals.
Regulatory Flags
Frequently Asked Questions
Is CI 77163 safe in cosmetics?
Bismuth oxychloride is a permitted colorant with negligible systemic absorption, though sensitization potential exists; skin irritation and tingling sensations may occur in sensitive individuals. The EU classifies CI 77163 as "permitted". Safety rating: GOOD. 6 toxicological study endpoint(s) are available in our database.
Is CI 77163 allowed in the EU?
CI 77163 EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.
What does CI 77163 do in cosmetics?
CI 77163 functions as: Colorant, opacifying agent with pearlescent/shimmer effect. It is classified as a cosmetic ingredient in our database. CAS number: 7787-59-9.
What is the Margin of Safety for CI 77163?
adequate The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.
What is the NOAEL for CI 77163?
The NOAEL (No Observed Adverse Effect Level) for CI 77163 is 500 mg/kg bw/day based on a dermal study via dermal route in code:3484. A total of 6 study endpoints are available. Source: REACH.
Compliance Tools
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Related Ingredients
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