Regulatory Status
For full compliance data across 55 jurisdictions, use the Substance Compliance tool.
Safety Data
Calculate MoS for your specific formulation with the MoS Calculator.
Toxicological Studies
10 study endpoints found for Acid Blue 9. NOAEL (No Observed Adverse Effect Level) values are used to calculate the Margin of Safety per SCCS methodology.
| Endpoint | Value | Route | Species | Study Type | Source |
|---|---|---|---|---|---|
| NOAEL | 1000 mg/kg bw/day | oral | rat | Multigeneration Reproductive | COSMOS_DB |
| NOAEL | 2000 mg/kg bw/day | oral | rat | Reproductive-developmental | COSMOS_DB |
| NOAEL | 1000 mg/kg bw/day | oral | rat | Chronic | COSMOS_DB |
| NOAEL | 1000 mg/kg bw/day | oral | rat | Carcinogenicity | COSMOS_DB |
| NOAEL | 250 mg/kg bw/day | oral | mouse | Carcinogenicity | COSMOS_DB |
| NOAEL | 1500 mg/kg bw/day | oral | rat | Chronic | COSMOS_DB |
| NOAEL | 200 mg/kg bw/day | oral | rabbit | Developmental | COSMOS_DB |
| NOAEL | 2500 mg/kg bw/day | oral | rat | Chronic | COSMOS_DB |
| NOAEL | 1000 mg/kg bw/day | oral | dog | Chronic | COSMOS_DB |
| NOAEL | 2000 mg/kg bw/day | oral | rat | Reproductive | COSMOS_DB |
Sensitization Profile
Contact sensitization data for Acid Blue 9 based on clinical patch test studies and IFRA standards.
Source: SCCS; IVDK
Expert Verdict
One of the most broadly approved cosmetic colorants globally; eye-area safe in US
Regulatory Flags
Frequently Asked Questions
Is Acid Blue 9 safe in cosmetics?
One of the most broadly approved cosmetic colorants globally; eye-area safe in US The EU classifies Acid Blue 9 as "restricted". Safety rating: EXCELLENT. 10 toxicological study endpoint(s) are available in our database.
Is Acid Blue 9 allowed in the EU?
Acid Blue 9 EU regulatory status: restricted. This is based on EU Regulation 1223/2009 and its amendments.
What does Acid Blue 9 do in cosmetics?
Acid Blue 9 functions as: Colorant, Hair Dyeing. It is classified as a cosmetic ingredient in our database. CAS number: 3844-45-9.
What is the Margin of Safety for Acid Blue 9?
adequate The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.
What is the NOAEL for Acid Blue 9?
The NOAEL (No Observed Adverse Effect Level) for Acid Blue 9 is 1000 mg/kg bw/day based on a Multigeneration Reproductive study via oral route in rat. A total of 10 study endpoints are available. Source: COSMOS_DB.
Compliance Tools
Check Acid Blue 9 compliance across multiple jurisdictions:
Related Ingredients
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