cis-3-Hexenyl Formate

INCI: CIS-3-HEXENYL FORMATE

CAS Number
33467-73-1
Function
Fragrance ingredient with green, unripe fruit, and fresh leaf notes
Safety Rating
GOOD

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status permitted
๐Ÿ‡บ๐Ÿ‡ธ US Status permitted
US Notes FEMA GRAS; RIFM safety assessed via read-across to cis-3-hexenyl acetate group

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
adequate
Dermal Absorption
low
Sensitization
low

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

Fragrance ingredient assessed as GRAS by FEMA; formic acid hydrolysis product presents irritation potential at high concentrations, though direct test data is limited and primarily relies on read-across to structurally similar cis-3-hexenyl acetate.

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Concern Level: Low

Regulatory Flags

fragrance-component ifra_fragrance fda_food_additive jecfa_safe

Frequently Asked Questions

Is cis-3-Hexenyl Formate safe in cosmetics?

Fragrance ingredient assessed as GRAS by FEMA; formic acid hydrolysis product presents irritation potential at high concentrations, though direct test data is limited and primarily relies on read-across to structurally similar cis-3-hexenyl acetate. The EU classifies cis-3-Hexenyl Formate as "permitted". Safety rating: GOOD.

Is cis-3-Hexenyl Formate allowed in the EU?

cis-3-Hexenyl Formate EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does cis-3-Hexenyl Formate do in cosmetics?

cis-3-Hexenyl Formate functions as: Fragrance ingredient with green, unripe fruit, and fresh leaf notes. It is classified as a cosmetic ingredient in our database. CAS number: 33467-73-1.

What is the Margin of Safety for cis-3-Hexenyl Formate?

adequate The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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