Is Diethylbenzene safe in cosmetics?
Diethylbenzene has a safety rating of "POOR" in our database. EU status: permitted. US status: permitted.
POOR
Cosmetic Ingredient
Diethylbenzene
INCI: DIETHYLBENZENE
Diethylbenzene (CAS 25340-17-4 (mixed isomers)) is a cosmetic cosmetic ingredient functioning as Solvent / fragrance ingredient. EU Regulation 1223/2009 status: permitted. Industrial safety data is also available in the chemical safety database.
View industrial chemical safety profile for CAS 25340-17-4 (mixed isomers) →
Function
Solvent / fragrance ingredient
Editorial assessment
POOR
Preliminary editorial note — not a computed safety verdict.
Regulatory Status
EU EU Status
permitted
US US Status
permitted
US Notes
Permitted — TSCA listed; no specific 21 CFR cosmetic restriction
For full compliance data across multiple jurisdictions, use the Substance Compliance tool.
Safety Data
Margin of Safety, dermal absorption, and sensitization profile summaries for Diethylbenzene.
Calculate MoS for your specific formulation with the MoS Calculator.
Editorial summary
Preliminary editorial summary for Diethylbenzene — not a computed safety verdict. See the sourced toxicological data above.
Regulatory Flags
fragrance-component
ifra_fragrance
NOAEL Studies Summary
View details ->Public NOAEL study rows linked to Diethylbenzene by CAS number or substance name.
Studies
9
Lowest NOAEL
5 mg/kg bw/day
Highest NOAEL
150 mg/kg bw/day
ECHA
Frequently Asked Questions
Is Diethylbenzene allowed in the EU?
Diethylbenzene EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.
What does Diethylbenzene do in cosmetics?
Diethylbenzene functions as: Solvent / fragrance ingredient. It is classified as a cosmetic ingredient in our database. CAS number: 25340-17-4 (mixed isomers).
Compliance Tools
Check Diethylbenzene compliance across multiple jurisdictions:
Ingredient Decoder
Paste a full ingredient list for instant analysis
82 Allergen Checker
Check for EU declarable fragrance allergens
Substance Compliance
Check compliance across multiple jurisdictions
MoS Calculator
Calculate Margin of Safety using SCCS methodology
Heavy Metal Limits
Compare limits across jurisdictions
Related Ingredients
2,6-Dimethyl-7-octen-2-ol (Dihydromyrcenol)
EXCELLENT
Same category
Fragrance (perfuming), masking
2-Ethoxy-2,6,6-Trimethyl-9-Methylenebicyclo[3.3.1]Nonane (Boisiris™)
EXCELLENT
Same category
Fragrance (rich woody, orris/iris roo...
3,6-Dimethyl-3-Octyl Acetate
EXCELLENT
Same category
Fragrance / Perfuming agent with flor...
3-Methyl-5-(2,2,3-Trimethyl-3-Cyclopentenyl)Pent-4-En-2-Ol (Sandalore)
EXCELLENT
Same category
Perfuming / Fragrance (sandalwood note)
4-Tert-Butylcyclohexyl Acetate
EXCELLENT
Same category
Fragrance
Acetoin
EXCELLENT
Same category
Skin conditioning, fragrance
1,2,4-Benzenetriacetate
POOR
Similar safety
Hair dye precursor (triacetyl ester o...
1,2,4-Trihydroxybenzene
POOR
Similar safety
Hair colorant (auto-oxidative dye)
1,3-Bis-(Isocyanatomethyl) Cyclohexane
POOR
Similar safety
Monomer / cross-linking agent used in...
1,4-Butanediol
POOR
Similar safety
Solvent, humectant, viscosity control...
1,6-Hexamethylene Diisocyanate (HDI)
POOR
Similar safety
Monomer and crosslinker in polymer sy...
1,6-Hexanediamine
POOR
Similar safety
Industrial chemical (nylon monomer); ...
DIETHANOLAMINE
MODERATE
Browse nearby
Buffering
DIETHYL PHTHALATE
GOOD
Browse nearby
Denaturant, Film Forming, Fragrance, ...
DIETHYL TOLUAMIDE
GOOD
Browse nearby
Skin Protecting
Is Diethylbenzene in Your Products?
Scan any product label with Piro — our free ingredient scanner. Point your camera at the ingredients list and get instant safety scores for every ingredient.
Try Piro Free →Analyze Your Full Ingredient List
Paste any INCI list into the Decoder for instant safety analysis, or calculate the Margin of Safety for Diethylbenzene in your formulation.