Citrus Reticulata Peel Extract

INCI: CITRUS RETICULATA (TANGERINE) PEEL EXTRACT

CAS Number
Not specifically assigned (related entries share genus-level CAS)
Function
Skin-Conditioning Agent — Miscellaneous
Safety Rating
GOOD

Regulatory Status

🇪🇺 EU Status permitted
🇺🇸 US Status permitted
US Notes Not restricted by FDA. Tangerine peel extracts and distillates are GRAS per 21 CFR 182.20.

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
adequate
Dermal Absorption
negligible
Sensitization
low

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

Furocoumarin content (5-MOP) should be monitored; supplier testing showed none detected. In vitro phototoxicity negative per OECD TG 432. Genotoxicity negative in reverse mutation assay at 3%. Slight, well-defined erythema observed in 3/30 subjects at 48 hours with occlusion (3.06% in formulation), resolving by 24 hours.

⚠️
Concern Level: Low

Regulatory Flags

plant-extract

Frequently Asked Questions

Is Citrus Reticulata Peel Extract safe in cosmetics?

Furocoumarin content (5-MOP) should be monitored; supplier testing showed none detected. In vitro phototoxicity negative per OECD TG 432. Genotoxicity negative in reverse mutation assay at 3%. Slight, well-defined erythema observed in 3/30 subjects at 48 hours with occlusion (3.06% in formulation), resolving by 24 hours. The EU classifies Citrus Reticulata Peel Extract as "permitted". Safety rating: GOOD.

Is Citrus Reticulata Peel Extract allowed in the EU?

Citrus Reticulata Peel Extract EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Citrus Reticulata Peel Extract do in cosmetics?

Citrus Reticulata Peel Extract functions as: Skin-Conditioning Agent — Miscellaneous. It is classified as a cosmetic ingredient in our database. CAS number: Not specifically assigned (related entries share genus-level CAS).

What is the Margin of Safety for Citrus Reticulata Peel Extract?

adequate The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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