Is Matricaria Chamomilla Extract safe in cosmetics?
Matricaria Chamomilla Extract has a safety rating of "GOOD" in our database. EU status: permitted. US status: permitted. 4 toxicological study endpoint(s) are available in our database.
Matricaria Chamomilla Extract
INCI: CHAMOMILLA RECUTITA (MATRICARIA) EXTRACT
Matricaria Chamomilla Extract (CAS 84082-60-0) is a cosmetic cosmetic ingredient functioning as Skin conditioning, Fragrance, Soothing. Reported NOAEL =200 mg/kg/d in rat (CIR_vision_codex); EU Regulation 1223/2009 status: permitted. Industrial safety data is also available in the chemical safety database. Same-CAS public records also appear in industrial chemical safety and pharmaceutical data.
View industrial chemical safety profile for CAS 84082-60-0 →
Auto-generated CPSR Part A draft with source citations
Cross-Vertical Regulatory Divergence
Matricaria Chamomilla Extract is classified GHS Danger (H304, H315, H317, H412) in the chemicals database but is allowed in EU cosmetics.
Source: Cosmetics: ingredients.eu_status; Chemicals: ghs_classifications.signal_word/hazard_statement_code
Function
Skin conditioning, Fragrance, Soothing
Safety Rating
GOOD
Regulatory Status
EU EU Status
permitted
US US Status
permitted
US Notes
CIR panel concluded safe in present practices of use and concentration when formulated to be non-sensitizing; typical use up to 0.8%
For full compliance data across multiple jurisdictions, use the Substance Compliance tool.
Safety Data
Margin of Safety, dermal absorption, and sensitization profile summaries for Matricaria Chamomilla Extract.
Calculate MoS for your specific formulation with the MoS Calculator.
Toxicological Studies
4 study endpoints found for Matricaria Chamomilla Extract. NOAEL (No Observed Adverse Effect Level) values are used to calculate the Margin of Safety per SCCS methodology.
| Endpoint | Value | Route | Species | Study Type | Source |
|---|---|---|---|---|---|
| NOAEL | =200 mg/kg/d | oral | rat | oral toxicity | CIR_vision_codex |
| NOAEL | =200 mg/kg/d | oral | rat | oral toxicity | CIR_vision_codex |
| NOAEL | =200 mg/kg/d | oral | rat | oral toxicity | CIR_vision_codex |
| NOAEL | =200 mg/kg/d | oral | rat | oral toxicity | CIR_vision_codex |
ECHA REACH Registration
European Chemicals Agency REACH dossier and Substances of Very High Concern listing.
Registration Type
Full
Tonnage Band
1 - 10 tonnes
Substance Type
SUBSTANCE
SVHC Candidate
No
Function Categories & List Membership
Cosmetic/Chemical Function Categories
Biocide
Regulatory List Membership (2)
EU Regulated in Personal Care
EU Restricted for Children (Cosmetics)
Expert Verdict
Expert safety assessment and concern-level summary for Matricaria Chamomilla Extract.
Regulatory Flags
plant-extract
soothing
anti-inflammatory
fragrance
skin-conditioning
chamomile
cir-safe
asteraceae
eu_children_restricted
NOAEL Studies Summary
View details ->Public NOAEL study rows linked to Matricaria Chamomilla Extract by CAS number or substance name.
Studies
4
Lowest NOAEL
200 mg/kg/d
Highest NOAEL
200 mg/kg/d
CIR_vision_codex
Chemical Function
Deodorizer
Softener and conditioner
Fragrance
Regulatory Lists
children; Europe; Personal care
children; Europe; Personal care - hair styling and care - shampoo
children; Europe; Personal care - specialized bath products - bubble bath
children; Europe; Personal care - dental care - toothpaste
Europe; Personal care - hair styling and care - shampoo-dandruff
Europe; Personal care
Europe; Personal care
Europe; Personal care
Europe; Personal care
Europe; Personal care
Europe; Personal care
Europe; Personal care
Europe; Personal care
Europe; Personal care
Europe; Personal care
Cross-Vertical Safety Context
Same-CAS public records found in pharmaceutical data.
SOURCE
ChEMBL / DrugCentral / FAERS
DB_PHARMA count match
Pharmaceutical Data
Same-CAS rows from the pharmaceutical spoke database.
Adverse Event Associations
58
Frequently Asked Questions
Is Matricaria Chamomilla Extract allowed in the EU?
Matricaria Chamomilla Extract EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.
What does Matricaria Chamomilla Extract do in cosmetics?
Matricaria Chamomilla Extract functions as: Skin conditioning, Fragrance, Soothing. It is classified as a cosmetic ingredient in our database. CAS number: 84082-60-0.
What is the NOAEL for Matricaria Chamomilla Extract?
The NOAEL (No Observed Adverse Effect Level) for Matricaria Chamomilla Extract is =200 mg/kg/d based on a oral toxicity study via oral route in rat. A total of 4 study endpoints are available. Source: CIR_vision_codex.
Is Matricaria Chamomilla Extract used outside cosmetics?
Matricaria Chamomilla Extract also appears in industrial chemical safety and pharmaceutical data. The cross-vertical cards on this page render same-CAS public rows from the matched databases.
Does Matricaria Chamomilla Extract have different safety status in cosmetics vs industrial chemicals?
Matricaria Chamomilla Extract is classified GHS Danger (H304, H315, H317, H412) in the chemicals database but is allowed in EU cosmetics.
Compliance Tools
Check Matricaria Chamomilla Extract compliance across multiple jurisdictions:
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82 Allergen Checker
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Substance Compliance
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MoS Calculator
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Heavy Metal Limits
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