Clinopodium Nepeta Extract (Lesser Calamint Extract)

INCI: CLINOPODIUM NEPETA EXTRACT

Clinopodium Nepeta Extract (Lesser Calamint Extract) (CAS 223748-11-6) is a cosmetic cosmetic ingredient functioning as Skin conditioning; Tonic; Antimicrobial; Anti-inflammatory. Extract obtained. EU Regulation 1223/2009 status: permitted. Industrial safety data is also available in the chemical safety database.

View industrial chemical safety profile for CAS 223748-11-6 →

Auto-generated CPSR Part A draft with source citations
Function
Skin conditioning; Tonic; Antimicrobial; Anti-inflammatory. Extract obtained from the aerial parts (flowers, leaves, stems) of Clinopodium nepeta (L.) Kuntze (syn. Calamintha nepeta), a perennial aromatic herb of the Lamiaceae family native to the Mediterranean region. Contains rosmarinic acid, luteolin, ursolic acid, pulegone, and other polyphenols with documented antioxidant, antimicrobial, and anti-inflammatory properties. A 2025 dermatoprotective study confirmed anti-elastase, anti-tyrosinase, and photoprotective activities. Essential oil from the plant contains pulegone as a major constituent. Functions in cosmetics as a skin conditioning and tonic agent.
Safety Rating
GOOD

Regulatory Status

EU EU Status permitted
US US Status permitted
US Notes Not specifically restricted by FDA for cosmetic use. The essential oil of this plant contains pulegone, a compound subject to IFRA restrictions; however, at the extract level used in cosmetics, pulegone levels are expected to be low. Standard cosmetic safety substantiation per 21 CFR required.

For full compliance data across multiple jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety, dermal absorption, and sensitization profile summaries for Clinopodium Nepeta Extract (Lesser Calamint Extract).

Calculate MoS for your specific formulation with the MoS Calculator.

Function Categories & List Membership

Cosmetic/Chemical Function Categories
Softener and conditioner

Expert Verdict

Expert safety assessment and concern-level summary for Clinopodium Nepeta Extract (Lesser Calamint Extract).

Regulatory Flags

plant-extract skin-conditioning antioxidant anti-inflammatory antimicrobial tonic lamiaceae rosmarinic-acid pulegone-monitor mediterranean-botanical

Chemical Function

Softener and conditioner

Frequently Asked Questions

Is Clinopodium Nepeta Extract (Lesser Calamint Extract) safe in cosmetics?

Clinopodium Nepeta Extract (Lesser Calamint Extract) has a safety rating of "GOOD" in our database. EU status: permitted. US status: permitted.

Is Clinopodium Nepeta Extract (Lesser Calamint Extract) allowed in the EU?

Clinopodium Nepeta Extract (Lesser Calamint Extract) EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Clinopodium Nepeta Extract (Lesser Calamint Extract) do in cosmetics?

Clinopodium Nepeta Extract (Lesser Calamint Extract) functions as: Skin conditioning; Tonic; Antimicrobial; Anti-inflammatory. Extract obtained from the aerial parts (flowers, leaves, stems) of Clinopodium nepeta (L.) Kuntze (syn. Calamintha nepeta), a perennial aromatic herb of the Lamiaceae family native to the Mediterranean region. Contains rosmarinic acid, luteolin, ursolic acid, pulegone, and other polyphenols with documented antioxidant, antimicrobial, and anti-inflammatory properties. A 2025 dermatoprotective study confirmed anti-elastase, anti-tyrosinase, and photoprotective activities. Essential oil from the plant contains pulegone as a major constituent. Functions in cosmetics as a skin conditioning and tonic agent.. It is classified as a cosmetic ingredient in our database. CAS number: 223748-11-6.

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