Moderate Cosmetic Ingredient NOAEL Data

Cocamidopropyl Dimethylamine

CAS Number
68140-01-2
Function
Anti-static agent; Emulsifier; Softener and conditioner; Surfactant (surface active agent)
Safety Rating
MODERATE

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status permitted
๐Ÿ‡บ๐Ÿ‡ธ US Status permitted
US Notes CIR: SQ - IJT 38(S1):39-69,2019

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
not established
Dermal Absorption
low
Sensitization
low

Calculate MoS for your specific formulation with the MoS Calculator.

Toxicological Studies

1 study endpoint found for Cocamidopropyl Dimethylamine. NOAEL (No Observed Adverse Effect Level) values are used to calculate the Margin of Safety per SCCS methodology.

Endpoint Value Route Species Study Type Source
NOAEL ca.60 mg/kg bw/day oral rat oral REACH

Expert Verdict

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Concern Level: Low

Frequently Asked Questions

Is Cocamidopropyl Dimethylamine safe in cosmetics?

Cocamidopropyl Dimethylamine has a safety rating of "MODERATE" in our database. EU status: permitted. US status: permitted. 1 toxicological study endpoint(s) are available in our database.

Is Cocamidopropyl Dimethylamine allowed in the EU?

Cocamidopropyl Dimethylamine EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Cocamidopropyl Dimethylamine do in cosmetics?

Cocamidopropyl Dimethylamine functions as: Anti-static agent; Emulsifier; Softener and conditioner; Surfactant (surface active agent). It is classified as a cosmetic ingredient in our database. CAS number: 68140-01-2.

What is the Margin of Safety for Cocamidopropyl Dimethylamine?

not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

What is the NOAEL for Cocamidopropyl Dimethylamine?

The NOAEL (No Observed Adverse Effect Level) for Cocamidopropyl Dimethylamine is ca.60 mg/kg bw/day based on a oral study via oral route in rat. Source: REACH.

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