Regulatory Status
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Safety Data
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Expert Verdict
Nitrosamine formation risk: Morpholine is readily nitrosated to form N-nitrosomorpholine (NMOR), a potent carcinogen. Must test for N-nitroso impurities. Free morpholine content must be controlled per EU Annex III restrictions. CIR analogue review concluded insufficient safety data for leave-on use. DMAPA impurity risk present.
Frequently Asked Questions
Is Cocamidopropyl Morpholine safe in cosmetics?
Nitrosamine formation risk: Morpholine is readily nitrosated to form N-nitrosomorpholine (NMOR), a potent carcinogen. Must test for N-nitroso impurities. Free morpholine content must be controlled per EU Annex III restrictions. CIR analogue review concluded insufficient safety data for leave-on use. DMAPA impurity risk present. The EU classifies Cocamidopropyl Morpholine as "restricted". Safety rating: MODERATE.
Is Cocamidopropyl Morpholine allowed in the EU?
Cocamidopropyl Morpholine EU regulatory status: restricted. Maximum allowed concentration: 0.1%. This is based on EU Regulation 1223/2009 and its amendments.
What does Cocamidopropyl Morpholine do in cosmetics?
Cocamidopropyl Morpholine functions as: Antistatic, hair conditioning. It is classified as a cosmetic ingredient in our database. CAS number: Not publicly assigned.
What is the Margin of Safety for Cocamidopropyl Morpholine?
not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.
Compliance Tools
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Related Ingredients
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