Regulatory Status
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Safety Data
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Expert Verdict
Acute oral LD50: 500–1000 mg/kg (rats); acute dermal LD50: >2174 mg/kg (rats); 28-day oral study showed hemolytic anemia at ≥150 mg/kg/day (NOEL=15 mg/kg/day); 81.5% concentration caused severe rabbit eye irritation; no reproductive/developmental toxicity data; leave-on use flagged as data-deficient by CIR.
Frequently Asked Questions
Is Cocamine Oxide safe in cosmetics?
Acute oral LD50: 500–1000 mg/kg (rats); acute dermal LD50: >2174 mg/kg (rats); 28-day oral study showed hemolytic anemia at ≥150 mg/kg/day (NOEL=15 mg/kg/day); 81.5% concentration caused severe rabbit eye irritation; no reproductive/developmental toxicity data; leave-on use flagged as data-deficient by CIR. The EU classifies Cocamine Oxide as "permitted". Safety rating: GOOD.
Is Cocamine Oxide allowed in the EU?
Cocamine Oxide EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.
What does Cocamine Oxide do in cosmetics?
Cocamine Oxide functions as: Surfactant – Foam boosting, Hydrotrope, Cleansing, Hair conditioning, Antistatic. It is classified as a cosmetic ingredient in our database. CAS number: 61788-90-7 (coco alkyldimethylamine oxide) ; Cocamidopropylamine Oxide variant: 68155-09-9.
What is the Margin of Safety for Cocamine Oxide?
adequate The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.
Compliance Tools
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Related Ingredients
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