Regulatory Status
For full compliance data across 55 jurisdictions, use the Substance Compliance tool.
Safety Data
Calculate MoS for your specific formulation with the MoS Calculator.
Toxicological Studies
4 study endpoints found for Acetylated Lanolin. NOAEL (No Observed Adverse Effect Level) values are used to calculate the Margin of Safety per SCCS methodology.
| Endpoint | Value | Route | Species | Study Type | Source |
|---|---|---|---|---|---|
| NOAEL | >=1000 mg/kg bw/day | oral | rat | oral | REACH |
| NOAEL | >=1000 mg/kg bw/day | oral | rat | oral | REACH |
| NOAEL | >=1000 mg/kg bw/day | oral | - | oral | REACH |
| NOAEL | >=1000 mg/kg bw/day | oral | - | oral | REACH |
Expert Verdict
CAS 61788-48-5 (EINECS 262-979-2). EU: Permitted, no concentration limit under Regulation 1223/2009. US: CIR safe (up to 7%). Low acute toxicity; potential for contact allergy on compromised skin only.
Regulatory Flags
Frequently Asked Questions
Is Acetylated Lanolin safe in cosmetics?
CAS 61788-48-5 (EINECS 262-979-2). EU: Permitted, no concentration limit under Regulation 1223/2009. US: CIR safe (up to 7%). Low acute toxicity; potential for contact allergy on compromised skin only. The EU classifies Acetylated Lanolin as "permitted". Safety rating: GOOD. 4 toxicological study endpoint(s) are available in our database.
Is Acetylated Lanolin allowed in the EU?
Acetylated Lanolin EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.
What does Acetylated Lanolin do in cosmetics?
Acetylated Lanolin functions as: Emollient; occlusive agent; hair conditioner. It is classified as a Emollient in our database. CAS number: 61788-48-5.
What is the Margin of Safety for Acetylated Lanolin?
adequate The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.
What is the NOAEL for Acetylated Lanolin?
The NOAEL (No Observed Adverse Effect Level) for Acetylated Lanolin is >=1000 mg/kg bw/day based on a oral study via oral route in rat. A total of 4 study endpoints are available. Source: REACH.
Compliance Tools
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Related Ingredients
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