Cocaminobutyric Acid

INCI: COCAMINOBUTYRIC ACID

CAS Number
68649-05-8 (N-coco alkyl derivatives of 4-aminobutyric acid)
Function
Surfactant – Cleansing, Hair conditioning agent (amphoteric surfactant)
Safety Rating
MODERATE

Regulatory Status

🇪🇺 EU Status permitted
🇺🇸 US Status permitted
US Notes FDA permitted; no specific restrictions

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
not established
Dermal Absorption
low
Sensitization
low

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

Limited published safety data — CPSR assessor will require read-across justification from structurally analogous amphoteric surfactants (e.g., cocaminopropionic acid, cocamidopropyl betaine); specify purity and impurity profile; no SCCS opinion available

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Concern Level: Moderate

Frequently Asked Questions

Is Cocaminobutyric Acid safe in cosmetics?

Limited published safety data — CPSR assessor will require read-across justification from structurally analogous amphoteric surfactants (e.g., cocaminopropionic acid, cocamidopropyl betaine); specify purity and impurity profile; no SCCS opinion available The EU classifies Cocaminobutyric Acid as "permitted". Safety rating: MODERATE.

Is Cocaminobutyric Acid allowed in the EU?

Cocaminobutyric Acid EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Cocaminobutyric Acid do in cosmetics?

Cocaminobutyric Acid functions as: Surfactant – Cleansing, Hair conditioning agent (amphoteric surfactant). It is classified as a cosmetic ingredient in our database. CAS number: 68649-05-8 (N-coco alkyl derivatives of 4-aminobutyric acid).

What is the Margin of Safety for Cocaminobutyric Acid?

not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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