Cocoyl Hydrolyzed Collagen

INCI: COCOYL HYDROLYZED COLLAGEN

CAS Number
68920-65-0 (Potassium salt); 68952-16-9 (TEA salt); 68188-38-5 (Sodium salt)
Function
Hair conditioning agent, skin conditioning agent, surfactant cleansing
Safety Rating
MODERATE

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status permitted
๐Ÿ‡บ๐Ÿ‡ธ US Status permitted
US Notes FDA-permitted. CIR originally concluded safe (1983), reaffirmed (2002). Reopened June 2024 for re-evaluation of sensitization and photosensitization data.

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
not established
Dermal Absorption
low
Sensitization
moderate

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

Active CIR re-review opened June 2024: Sensitization observed at 10% in HRIPT; photosensitization reported in at least 1 subject; use has declined from 64 formulations (2001) to 2 (2023 VCRP). Undiluted material causes moderate-to-severe ocular irritation. Animal-derived collagen origin must be declared per some jurisdictions.

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Concern Level: Moderate

Regulatory Flags

potential-allergen

Frequently Asked Questions

Is Cocoyl Hydrolyzed Collagen safe in cosmetics?

Active CIR re-review opened June 2024: Sensitization observed at 10% in HRIPT; photosensitization reported in at least 1 subject; use has declined from 64 formulations (2001) to 2 (2023 VCRP). Undiluted material causes moderate-to-severe ocular irritation. Animal-derived collagen origin must be declared per some jurisdictions. The EU classifies Cocoyl Hydrolyzed Collagen as "permitted". Safety rating: MODERATE.

Is Cocoyl Hydrolyzed Collagen allowed in the EU?

Cocoyl Hydrolyzed Collagen EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Cocoyl Hydrolyzed Collagen do in cosmetics?

Cocoyl Hydrolyzed Collagen functions as: Hair conditioning agent, skin conditioning agent, surfactant cleansing. It is classified as a cosmetic ingredient in our database. CAS number: 68920-65-0 (Potassium salt); 68952-16-9 (TEA salt); 68188-38-5 (Sodium salt).

What is the Margin of Safety for Cocoyl Hydrolyzed Collagen?

not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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