Cycloartenyl Ferulate

INCI: CYCLOARTENYL FERULATE

CAS Number
21238-33-5 (individual compound); also referenced under 11042-64-1 as a component of γ-oryzanol
Function
Antioxidant, skin conditioning
Safety Rating
MODERATE

Regulatory Status

🇪🇺 EU Status permitted
🇺🇸 US Status permitted
US Notes Allowed - no prohibitions or restrictions

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
not established
Dermal Absorption
low
Sensitization
low

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

No major safety concerns identified. It is a naturally occurring phytosteryl ferulate with a well-characterized safety profile as a component of rice bran oil (γ-oryzanol). Molecular formula C₄₀H₅₈O₄ (MW 602.9 g/mol). It is one of the principal components of γ-oryzanol isolated from rice bran oil and Larix kaemferi bark. Possesses documented anti-oxidative, antiallergic, anti-inflammatory, and anticancer activities

⚠️
Concern Level: Moderate

Regulatory Flags

natural-origin

Frequently Asked Questions

Is Cycloartenyl Ferulate safe in cosmetics?

No major safety concerns identified. It is a naturally occurring phytosteryl ferulate with a well-characterized safety profile as a component of rice bran oil (γ-oryzanol). Molecular formula C₄₀H₅₈O₄ (MW 602.9 g/mol). It is one of the principal components of γ-oryzanol isolated from rice bran oil and Larix kaemferi bark. Possesses documented anti-oxidative, antiallergic, anti-inflammatory, and anticancer activities The EU classifies Cycloartenyl Ferulate as "permitted". Safety rating: MODERATE.

Is Cycloartenyl Ferulate allowed in the EU?

Cycloartenyl Ferulate EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Cycloartenyl Ferulate do in cosmetics?

Cycloartenyl Ferulate functions as: Antioxidant, skin conditioning. It is classified as a cosmetic ingredient in our database. CAS number: 21238-33-5 (individual compound); also referenced under 11042-64-1 as a component of γ-oryzanol.

What is the Margin of Safety for Cycloartenyl Ferulate?

not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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