Good Cosmetic Ingredient NOAEL Data

CYCLOHEXYL METHACRYLATE

CAS Number
101-43-9
Function
Film Forming
Safety Rating
GOOD

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status Permitted
๐Ÿ‡บ๐Ÿ‡ธ US Status restricted
US Notes CIR: SQ - IJT 24(Suppl 5):53-100, 2005

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Toxicological Studies

8 study endpoints found for CYCLOHEXYL METHACRYLATE. NOAEL (No Observed Adverse Effect Level) values are used to calculate the Margin of Safety per SCCS methodology.

Endpoint Value Route Species Study Type Source
NOAEL 300 mg/kg bw/day oral rat oral REACH
NOAEL 300 mg/kg bw/day oral rat oral REACH
NOAEL >=90.3 mg/kg bw/day oral rat oral REACH
NOAEL 462 mg/kg bw/day oral code:3544 oral REACH
NOAEL 143 mg/kg bw/day oral rat oral REACH
NOAEL 143 mg/kg bw/day oral - oral REACH
NOAEL 462 mg/kg bw/day oral - oral REACH
NOAEL >=90.3 mg/kg bw/day oral - oral REACH

Expert Verdict

CYCLOHEXYL METHACRYLATE is listed in the EU CosIng database with functions: Film Forming It is permitted in the EU without specific restrictions.

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Concern Level: Low

Regulatory Flags

cosing-sourced eu-permitted needs-enrichment

Frequently Asked Questions

Is CYCLOHEXYL METHACRYLATE safe in cosmetics?

CYCLOHEXYL METHACRYLATE is listed in the EU CosIng database with functions: Film Forming It is permitted in the EU without specific restrictions. The EU classifies CYCLOHEXYL METHACRYLATE as "Permitted". Safety rating: GOOD. 8 toxicological study endpoint(s) are available in our database.

Is CYCLOHEXYL METHACRYLATE allowed in the EU?

CYCLOHEXYL METHACRYLATE EU regulatory status: Permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does CYCLOHEXYL METHACRYLATE do in cosmetics?

CYCLOHEXYL METHACRYLATE functions as: Film Forming. It is classified as a cosmetic ingredient in our database. CAS number: 101-43-9.

What is the NOAEL for CYCLOHEXYL METHACRYLATE?

The NOAEL (No Observed Adverse Effect Level) for CYCLOHEXYL METHACRYLATE is 300 mg/kg bw/day based on a oral study via oral route in rat. A total of 8 study endpoints are available. Source: REACH.

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