NOAEL Studies Cosmetic Ingredient

Cyclopentasiloxane NOAEL Studies

INCI: CYCLOPENTASILOXANE

CAS: 541-02-6

Raw No Observed Adverse Effect Level endpoint records grouped by source. This page does not render calculated Margin of Safety values.

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NTP ICE acute inhalation 2 endpoints
Source Endpoint Type Value Unit Species Route Duration Study Type Reference
NTP ICE acute inhalation LC50 >8.2595 mg/L - Inhalation Duration=4 hr In Vivo; AcuteInhalNICEATM; Rat Acute Inhalation Toxicity sheet=Data; excel_row=1080; Record_ID=acute_inhalation_737; Data_Type=In Vivo; Internal_Data_Source=AcuteInhalNICEATM; Mixture=Chemical; DTXSID=DTXSID1027184; Assay=Rat Acute Inhalation Toxicity; Endpoint=LC50; Response_Modifier=>; Response=8.2595; Response_Unit=mg/L; Reference=REACH; URL=https://echa.europa.eu/registration-dossier/-/registered-dossier/14807/7/3/3/?documentUUID=68f583cf-b552-49f8-bd36-0499bb1fcf6d; URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID1027184
NTP ICE acute inhalation LC50 8.67 mg/L - Inhalation Duration=4 hr In Vivo; AcuteInhalNICEATM; Rat Acute Inhalation Toxicity sheet=Data; excel_row=1081; Record_ID=acute_inhalation_777; Data_Type=In Vivo; Internal_Data_Source=AcuteInhalNICEATM; Mixture=Chemical; DTXSID=DTXSID1027184; Assay=Rat Acute Inhalation Toxicity; Endpoint=LC50; Response=8.67; Response_Unit=mg/L; Reference=REACH; URL=https://echa.europa.eu/registration-dossier/-/registered-dossier/14807/7/3/3/?documentUUID=d60ea98d-93ea-4930-ab1e-35238e818ff4; URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID1027184
NTP ICE acute oral 4 endpoints
Source Endpoint Type Value Unit Species Route Duration Study Type Reference
NTP ICE acute oral LD50 >5000 mg/kg bw Rat oral acute Rat Acute Oral Toxicity record_id=acute_oral_7438; row=2792; data_type=In Vivo; mixture=Chemical; chemical_name=Decamethylcyclopentasiloxane; preferred_name=Decamethylcyclopentasiloxane; dtxsid=DTXSID1027184; url_comptox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID1027184; source_file=acute_oral.xlsx
NTP ICE acute oral LD50 >20000 mg/kg bw Rat oral acute Rat Acute Oral Toxicity record_id=acute_oral_7440; row=2793; data_type=In Vivo; mixture=Chemical; chemical_name=Decamethylcyclopentasiloxane; preferred_name=Decamethylcyclopentasiloxane; dtxsid=DTXSID1027184; url_comptox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID1027184; source_file=acute_oral.xlsx
NTP ICE acute oral LD50 >24134 mg/kg bw Rat oral acute Rat Acute Oral Toxicity record_id=acute_oral_7442; row=2795; data_type=In Vivo; mixture=Chemical; chemical_name=Decamethylcyclopentasiloxane; preferred_name=Decamethylcyclopentasiloxane; dtxsid=DTXSID1027184; url_comptox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID1027184; source_file=acute_oral.xlsx
NTP ICE acute oral LD50 >61440 mg/kg bw Rat oral acute Rat Acute Oral Toxicity record_id=acute_oral_7444; row=2794; data_type=In Vivo; mixture=Chemical; chemical_name=Decamethylcyclopentasiloxane; preferred_name=Decamethylcyclopentasiloxane; dtxsid=DTXSID1027184; url_comptox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID1027184; source_file=acute_oral.xlsx
NTP ICE adme parameters 1 endpoint
Source Endpoint Type Value Unit Species Route Duration Study Type Reference
NTP ICE adme parameters Clint 0 uL/min/10^6 cells Human - - Measured; httk, Human Hepatic Intrinsic Clearance sheet=Data; excel_row=590; Record_ID=adme_parameters_963; Data_Type=Measured; DTXSID=DTXSID1027184; Assay=httk, Human Hepatic Intrinsic Clearance; Endpoint=Clint; Response=0.0; Response_Unit=ul/min/10^6 cells; Species=Human; Reference=httk2.3.1, Wambaugh 2019; URL=https://cran.r-project.org/web/packages/httk/index.html; URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID1027184
NTP ICE endocrine 1 endpoint
Source Endpoint Type Value Unit Species Route Duration Study Type Reference
NTP ICE endocrine Model Score 0 unitless - - - ARPathway2016; AR Pathway Model, Antagonist sheet=Integrated_approaches; excel_row=7408; RecordID=ARPathway2016_1303; DatasetName=ARPathway2016; DTXSID=DTXSID1027184; Assay=AR Pathway Model, Antagonist; Endpoint=Model Score; Response=0; Response_Unit=Unitless; URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID1027184
NTP ICE eye irritation 3 endpoints
Source Endpoint Type Value Unit Species Route Duration Study Type Reference
NTP ICE eye irritation Intensity 0.02 %/sec - Ocular - In Vitro; Vitrigel sheet=Data; excel_row=598; Record_ID=eye_irritation_1328; Data_Type=In Vitro; Mixture=Chemical; DTXSID=DTXSID1027184; Assay=Vitrigel; Endpoint=Intensity; Response=0.02; Response_Unit=%/sec; PMID=26472347.0; Reference=Yamaguchi et al. 2016; URL=10.1002/jat.3254; URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID1027184
NTP ICE eye irritation Lag time >180 s - Ocular - In Vitro; Vitrigel sheet=Data; excel_row=597; Record_ID=eye_irritation_1328; Data_Type=In Vitro; Mixture=Chemical; DTXSID=DTXSID1027184; Assay=Vitrigel; Endpoint=Lag time; Response_Modifier=>; Response=180; Response_Unit=sec; PMID=26472347.0; Reference=Yamaguchi et al. 2016; URL=10.1002/jat.3254; URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID1027184
NTP ICE eye irritation Plateau level 0 % - Ocular - In Vitro; Vitrigel sheet=Data; excel_row=599; Record_ID=eye_irritation_1328; Data_Type=In Vitro; Mixture=Chemical; DTXSID=DTXSID1027184; Assay=Vitrigel; Endpoint=Plateau level; Response=0; Response_Unit=%; PMID=26472347.0; Reference=Yamaguchi et al. 2016; URL=10.1002/jat.3254; URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID1027184
SCCS Opinion 14 endpoints
Source Endpoint Type Value Unit Species Route Duration Study Type Reference
SCCS Opinion NOAEL =5 ppm rat inhalation 14-day NOAEL study p.23
SCCS Opinion NOAEL =10 % rat oral - NOAEL study (ref 45), p.40
SCCS Opinion NOAEL =12 - - - - NOAEL study p.61
SCCS Opinion NOAEL =17.8 mg/kg bw/day - inhalation - NOAEL study (Ref 3), p.68
SCCS Opinion NOAEL =25 ppm rat inhalation 5 days NOAEL study p.22
SCCS Opinion NOAEL =25 - - - - NOAEL study p.25
SCCS Opinion NOAEL =35 - - - - reproductive toxicity p.35
SCCS Opinion NOAEL =48 % rat oral 5 days NOAEL study p.21
SCCS Opinion NOAEL =96 ppm rat inhalation 28 days irritation p.23
SCCS Opinion NOAEL =100 mg/kg bw/d - oral - irritation p.25
SCCS Opinion NOAEL =100 mg/kg bw - oral subchronic repeated dose toxicity (ref 45), p.27
SCCS Opinion NOAEL =100 mg/kg rat oral 3-month carcinogenicity p.50
SCCS Opinion NOAEL =160 ppm - - developmental reproductive toxicity Ref.: 51, Siddiqui et al, p.35
SCCS Opinion NOAEL =1000 mg/kg bw/d - oral - irritation p.25
ECHA 14 endpoints
Source Endpoint Type Value Unit Species Route Duration Study Type Reference
ECHA NOAEC =81 mg/m3 Rat inhalation short-term; 4 weeks short-term QUALITY=4 (not assignable); STORED_SOURCE_RECORD=https://clowder.edap-cluster.com/files/66059786e4b063812d6fa765; RECORD_SOURCE_LEVEL=Extraction document; SOURCE_URL=https://echa.europa.eu/; SUBSOURCE_URL=https://echa.europa.eu/registration-dossier/-/registered-dossier/14807/7/6/3?documentUUID=3f067151-9a94-44e1-b90d-29fd842b1c00; YEAR=1999; ORIGINAL_YEAR=1999; STUDY_GROUP=ECHA IUCLID:15827217:M/F:--; QC_CATEGORY=Programmatically extracted from structured data source; Source overall passed QC, but this record was not manually checked; QC_STATUS=not determined; SOURCE_HASH=ToxValhc_cefab6728a42780358957f208a76061a
ECHA NOAEC =606.58 mg/m3 Rat inhalation chronic; 6 months chronic QUALITY=1 (reliable without restriction); STORED_SOURCE_RECORD=https://clowder.edap-cluster.com/files/66059786e4b063812d6fa765; RECORD_SOURCE_LEVEL=Extraction document; SOURCE_URL=https://echa.europa.eu/; SUBSOURCE_URL=https://echa.europa.eu/registration-dossier/-/registered-dossier/14807/7/6/3?documentUUID=3f067151-9a94-44e1-b90d-29fd842b1c00; YEAR=1999; ORIGINAL_YEAR=1999; STUDY_GROUP=ECHA IUCLID:15829384:M/F:--; QC_CATEGORY=Programmatically extracted from structured data source; Source overall passed QC, but this record was not manually checked; QC_STATUS=not determined; SOURCE_HASH=ToxValhc_82ad1e93a48bed08813b28bc6709cf85
ECHA NOAEC >=1819.74 mg/m3 Rat inhalation short-term; 28 days short-term QUALITY=1 (reliable without restriction); STORED_SOURCE_RECORD=https://clowder.edap-cluster.com/files/66059786e4b063812d6fa765; RECORD_SOURCE_LEVEL=Extraction document; SOURCE_URL=https://echa.europa.eu/; SUBSOURCE_URL=https://echa.europa.eu/registration-dossier/-/registered-dossier/14807/7/6/3?documentUUID=3f067151-9a94-44e1-b90d-29fd842b1c00; YEAR=1999; ORIGINAL_YEAR=1999; STUDY_GROUP=ECHA IUCLID:15828132:M/F:--; QC_CATEGORY=Programmatically extracted from structured data source; Source overall passed QC, but this record was not manually checked; QC_STATUS=not determined; SOURCE_HASH=ToxValhc_844d5d23c463430cba0b6512089091f0
ECHA NOAEC >=2350 mg/m3 Rat inhalation short-term; 4 weeks short-term QUALITY=1 (reliable without restriction); STORED_SOURCE_RECORD=https://clowder.edap-cluster.com/files/66059786e4b063812d6fa765; RECORD_SOURCE_LEVEL=Extraction document; SOURCE_URL=https://echa.europa.eu/; SUBSOURCE_URL=https://echa.europa.eu/registration-dossier/-/registered-dossier/14807/7/6/3?documentUUID=3f067151-9a94-44e1-b90d-29fd842b1c00; YEAR=1999; ORIGINAL_YEAR=1999; STUDY_GROUP=ECHA IUCLID:15827644:M/F:--; QC_CATEGORY=Programmatically extracted from structured data source; Source overall passed QC, but this record was not manually checked; QC_STATUS=not determined; SOURCE_HASH=ToxValhc_bd06ee632a67737b80cc8e5603e6a5f6
ECHA NOAEC >=2426.32 mg/m3 Rat inhalation - chronic QUALITY=1 (reliable without restriction); STORED_SOURCE_RECORD=https://clowder.edap-cluster.com/files/66a7c823e4b0a7c65d216e7d; RECORD_SOURCE_LEVEL=Extraction document; SOURCE_URL=https://echa.europa.eu/; SUBSOURCE_URL=https://echa.europa.eu/registration-dossier/-/registered-dossier/14807/7/8?documentUUID=3f067151-9a94-44e1-b90d-29fd842b1c00; YEAR=1999; ORIGINAL_YEAR=1999; STUDY_GROUP=ECHA IUCLID:15816749:M:--; QC_CATEGORY=Programmatically extracted from structured data source; Source overall passed QC, but this record was not manually checked; QC_STATUS=not determined; SOURCE_HASH=ToxValhc_d1b1a4f9dd166c37bd7184779f65f402
ECHA NOAEC >=2441.48 mg/m3 Rat inhalation - developmental GUIDELINE=OECD Guideline 414 (Prenatal Developmental Toxicity Study); QUALITY=1 (reliable without restriction); STORED_SOURCE_RECORD=https://clowder.edap-cluster.com/files/66a7d1ebe4b0a7c65d230aad; RECORD_SOURCE_LEVEL=Extraction document; SOURCE_URL=https://echa.europa.eu/; SUBSOURCE_URL=https://echa.europa.eu/registration-dossier/-/registered-dossier/14807/7/9/3?documentUUID=3f067151-9a94-44e1-b90d-29fd842b1c00; YEAR=1999; ORIGINAL_YEAR=1999; STUDY_GROUP=ECHA IUCLID:15821002:M/F:-fetal; QC_CATEGORY=Programmatically extracted from structured data source; Source overall passed QC, but this record was not manually checked; QC_STATUS=not determined; SOURCE_HASH=ToxValhc_00b7a8e494f59cb9c4ed7d5366057bed
ECHA NOAEC >=3396.85 mg/m3 Rat inhalation subchronic; 3 months subchronic QUALITY=1 (reliable without restriction); STORED_SOURCE_RECORD=https://clowder.edap-cluster.com/files/67c61fa0e4b096bca877e2a6; RECORD_SOURCE_LEVEL=Extraction document; SOURCE_URL=https://echa.europa.eu/; SUBSOURCE_URL=https://echa.europa.eu/registration-dossier/-/registered-dossier/14807/7/6/3?documentUUID=3f067151-9a94-44e1-b90d-29fd842b1c00; YEAR=1999; ORIGINAL_YEAR=1999; STUDY_GROUP=ECHA IUCLID:15826912:M/F:--; QC_CATEGORY=Programmatically extracted from structured data source; Source overall passed QC, but this record was not manually checked; QC_STATUS=not determined; SOURCE_HASH=ToxValhc_2784f40136b95a8634c1d515a6e0bc5c
ECHA NOAEL >=960 mg/kg bw/day Rabbit dermal short-term; 3 weeks short-term QUALITY=4 (not assignable); STORED_SOURCE_RECORD=https://clowder.edap-cluster.com/files/67c61d4be4b096bca877537f; RECORD_SOURCE_LEVEL=Extraction document; SOURCE_URL=https://echa.europa.eu/; SUBSOURCE_URL=https://echa.europa.eu/registration-dossier/-/registered-dossier/14807/7/6/4?documentUUID=3f067151-9a94-44e1-b90d-29fd842b1c00; YEAR=1999; ORIGINAL_YEAR=1999; STUDY_GROUP=ECHA IUCLID:15826119:M/F:--; QC_CATEGORY=Programmatically extracted from structured data source; Source overall passed QC, but this record was not manually checked; QC_STATUS=not determined; SOURCE_HASH=ToxValhc_c87647551bf9847bd6d2259a259c1988
ECHA NOAEL >=1000 mg/kg bw/day Rabbit dermal short-term; 3 weeks short-term QUALITY=2 (reliable with restrictions); STORED_SOURCE_RECORD=https://clowder.edap-cluster.com/files/67c61de7e4b096bca8777898; RECORD_SOURCE_LEVEL=Extraction document; SOURCE_URL=https://echa.europa.eu/; SUBSOURCE_URL=https://echa.europa.eu/registration-dossier/-/registered-dossier/14807/7/6/4?documentUUID=3f067151-9a94-44e1-b90d-29fd842b1c00; YEAR=1999; ORIGINAL_YEAR=1999; STUDY_GROUP=ECHA IUCLID:15826335:M/F:--; QC_CATEGORY=Programmatically extracted from structured data source; Source overall passed QC, but this record was not manually checked; QC_STATUS=not determined; SOURCE_HASH=ToxValhc_ce99b5a1ce74b3e09fecb7d6e4f01abb
ECHA NOAEL >=1500 mg/kg bw/day Rat oral short-term; 28 days short-term QUALITY=1 (reliable without restriction); STORED_SOURCE_RECORD=https://clowder.edap-cluster.com/files/669eae65e4b0a7c65d1c8f9e; RECORD_SOURCE_LEVEL=Extraction document; SOURCE_URL=https://echa.europa.eu/; SUBSOURCE_URL=https://echa.europa.eu/registration-dossier/-/registered-dossier/14807/7/6/2?documentUUID=3f067151-9a94-44e1-b90d-29fd842b1c00; YEAR=1999; ORIGINAL_YEAR=1999; STUDY_GROUP=ECHA IUCLID:15834878:M/F:--; QC_CATEGORY=Programmatically extracted from structured data source; Source overall passed QC, but this record was not manually checked; QC_STATUS=not determined; SOURCE_HASH=ToxValhc_b40d2796f0cc60be6c3dc53cf6dfd2b0
ECHA NOAEL >=1600 mg/kg bw/day Rat dermal short-term; 28 days short-term QUALITY=1 (reliable without restriction); STORED_SOURCE_RECORD=https://clowder.edap-cluster.com/files/67c61d82e4b096bca8775fd6; RECORD_SOURCE_LEVEL=Extraction document; SOURCE_URL=https://echa.europa.eu/; SUBSOURCE_URL=https://echa.europa.eu/registration-dossier/-/registered-dossier/14807/7/6/4?documentUUID=3f067151-9a94-44e1-b90d-29fd842b1c00; YEAR=1999; ORIGINAL_YEAR=1999; STUDY_GROUP=ECHA IUCLID:15826187:M/F:--; QC_CATEGORY=Programmatically extracted from structured data source; Source overall passed QC, but this record was not manually checked; QC_STATUS=not determined; SOURCE_HASH=ToxValhc_20136e6ae53bf578601a4d8cceaf99a3
ECHA NOAEL >=2001.71 mg/m3 Rat inhalation - reproduction developmental QUALITY=1 (reliable without restriction); STORED_SOURCE_RECORD=https://clowder.edap-cluster.com/files/66a7c904e4b0a7c65d21b25c; RECORD_SOURCE_LEVEL=Extraction document; SOURCE_URL=https://echa.europa.eu/; SUBSOURCE_URL=https://echa.europa.eu/registration-dossier/-/registered-dossier/14807/7/9/2?documentUUID=3f067151-9a94-44e1-b90d-29fd842b1c00; YEAR=1999; ORIGINAL_YEAR=1999; STUDY_GROUP=ECHA IUCLID_dup_Toxicity Reproduction_15857585_15857697:M/F:P0-; QC_CATEGORY=Programmatically extracted from structured data source; Source overall passed QC, but this record was not manually checked; QC_STATUS=not determined; SOURCE_HASH=ToxValhc_83d1ce5c1280e261105bcce235404e26
ECHA NOAEL >=2426.32 mg/m3 Rat inhalation - reproduction developmental QUALITY=1 (reliable without restriction); STORED_SOURCE_RECORD=https://clowder.edap-cluster.com/files/66a7c904e4b0a7c65d21b228; RECORD_SOURCE_LEVEL=Extraction document; SOURCE_URL=https://echa.europa.eu/; SUBSOURCE_URL=https://echa.europa.eu/registration-dossier/-/registered-dossier/14807/7/9/2?documentUUID=3f067151-9a94-44e1-b90d-29fd842b1c00; YEAR=1999; ORIGINAL_YEAR=1999; STUDY_GROUP=ECHA IUCLID_dup_Toxicity Reproduction_15857585_15857697:M/F:P0-; QC_CATEGORY=Programmatically extracted from structured data source; Source overall passed QC, but this record was not manually checked; QC_STATUS=not determined; SOURCE_HASH=ToxValhc_49bc74fc906e021e94a2c92d1cbb4967
ECHA NOEC >2426.32 mg/m3 Rabbit inhalation - developmental GUIDELINE=OECD Guideline 414 (Prenatal Developmental Toxicity Study); QUALITY=1 (reliable without restriction); STORED_SOURCE_RECORD=https://clowder.edap-cluster.com/files/66a7d1ebe4b0a7c65d230ab7; RECORD_SOURCE_LEVEL=Extraction document; SOURCE_URL=https://echa.europa.eu/; SUBSOURCE_URL=https://echa.europa.eu/registration-dossier/-/registered-dossier/14807/7/9/3?documentUUID=3f067151-9a94-44e1-b90d-29fd842b1c00; YEAR=1999; ORIGINAL_YEAR=1999; STUDY_GROUP=ECHA IUCLID:15821857:M/F:-fetal; QC_CATEGORY=Programmatically extracted from structured data source; Source overall passed QC, but this record was not manually checked; QC_STATUS=not determined; SOURCE_HASH=ToxValhc_a12a16d2b995deadc14490f51fa1e4b1
ToxValDB GESTIS DNEL 2 endpoints
Source Endpoint Type Value Unit Species Route Duration Study Type Reference
ToxValDB GESTIS DNEL DNEL local =24.2 mg/m3 Human inhalation - Toxicity Value STORED_SOURCE_RECORD=https://clowder.edap-cluster.com/files/6543dd69e4b045b9ff7cd87e; RECORD_SOURCE_LEVEL=Extraction document; SOURCE_URL=https://www.dguv.de/ifa/gestis/gestis-dnel-liste/index-2.jsp; STUDY_GROUP=GESTIS DNEL_dup_-_15630925_15630926:-:--; QC_CATEGORY=Programmatically extracted from structured data source; Source overall passed QC, but this record was not manually checked; QC_STATUS=not determined; SOURCE_HASH=ToxValhc_43c0e689e9432fc5126c612e38214211
ToxValDB GESTIS DNEL DNEL systemic =97.3 mg/m3 Human inhalation - Toxicity Value STORED_SOURCE_RECORD=https://clowder.edap-cluster.com/files/6543dd69e4b045b9ff7cd87e; RECORD_SOURCE_LEVEL=Extraction document; SOURCE_URL=https://www.dguv.de/ifa/gestis/gestis-dnel-liste/index-2.jsp; STUDY_GROUP=GESTIS DNEL_dup_-_15630925_15630926:-:--; QC_CATEGORY=Programmatically extracted from structured data source; Source overall passed QC, but this record was not manually checked; QC_STATUS=not determined; SOURCE_HASH=ToxValhc_de0f4995b16cbbce7b54dc6ea89b1739
Regulatory source 20 endpoints
Source Endpoint Type Value Unit Species Route Duration Study Type Reference
Regulatory source - 5 ppm rat inhalation 14-day - p.23
Regulatory source - 10 % rat oral - - p.40
Regulatory source - 10 % - oral - - p.61
Regulatory source - 10 % - - - - p.61
Regulatory source - 12 - - - - - p.61
Regulatory source - 17.8 mg/kg bw/day - inhalation - - p.68
Regulatory source - 25 ppm rat inhalation 5 days - p.22
Regulatory source - 25 - - - - - p.25
Regulatory source - 48 % rat oral 5 days - p.21
Regulatory source carcinogenicity 100 mg/kg rat oral 3-month carcinogenicity p.50
Regulatory source carcinogenicity 100 mg/kg bw - oral 2-year carcinogenicity p.60
Regulatory source irritation 10 % rat oral - irritation p.61
Regulatory source irritation 96 ppm rat inhalation 28 days irritation p.23
Regulatory source irritation 100 mg/kg bw/d - oral - irritation p.25
Regulatory source irritation 1000 mg/kg bw/d - oral - irritation p.25
Regulatory source repeated dose toxicity 100 mg/kg bw - oral subchronic repeated dose toxicity p.27
Regulatory source repeated dose toxicity 100 mg/kg bw human oral chronic repeated dose toxicity p.60
Regulatory source reproductive toxicity 35 - - - - reproductive toxicity p.35
Regulatory source reproductive toxicity 160 ppm - - developmental reproductive toxicity p.35
Regulatory source reproductive toxicity 160 ppm rat inhalation 90 days reproductive toxicity p.67
openFDA substances 1 endpoint
Source Endpoint Type Value Unit Species Route Duration Study Type Reference
openFDA substances FDA UNII substance identifier 0THT5PCI0R UNII - - - chemical -