Cysteinyl Tripeptide-35

INCI: CYSTEINYL TRIPEPTIDE-35

CAS Number
Not assigned (synthetic peptide)
Function
Chelating Agent, Skin Protecting, Antiseborrhoeic (controls sebum production), Antioxidant
Safety Rating
MODERATE

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status permitted
๐Ÿ‡บ๐Ÿ‡ธ US Status permitted
US Notes Allowed. Synthetic peptides are permitted for cosmetic use; not on any FDA prohibited list

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
not established
Dermal Absorption
low
Sensitization
low

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

Generally considered low-risk as a synthetic tripeptide; limited published independent toxicological data; potential for peptide-related sensitivity at high concentrations is theoretically low. Composed of cysteine, glutamic acid, and glycine - structurally related to glutathione (a grandfathered INCI name for the same amino acid sequence). The "cysteinyl" prefix indicates an N-terminal cysteine modification. Functions as a mimetic of the endogenous antioxidant glutathione, supporting skin re...

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Concern Level: High

Frequently Asked Questions

Is Cysteinyl Tripeptide-35 safe in cosmetics?

Generally considered low-risk as a synthetic tripeptide; limited published independent toxicological data; potential for peptide-related sensitivity at high concentrations is theoretically low. Composed of cysteine, glutamic acid, and glycine - structurally related to glutathione (a grandfathered INCI name for the same amino acid sequence). The "cysteinyl" prefix indicates an N-terminal cysteine modification. Functions as a mimetic of the endogenous antioxidant glutathione, supporting skin re... The EU classifies Cysteinyl Tripeptide-35 as "permitted". Safety rating: MODERATE.

Is Cysteinyl Tripeptide-35 allowed in the EU?

Cysteinyl Tripeptide-35 EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Cysteinyl Tripeptide-35 do in cosmetics?

Cysteinyl Tripeptide-35 functions as: Chelating Agent, Skin Protecting, Antiseborrhoeic (controls sebum production), Antioxidant. It is classified as a cosmetic ingredient in our database. CAS number: Not assigned (synthetic peptide).

What is the Margin of Safety for Cysteinyl Tripeptide-35?

not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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