D-Heptapeptide-1

INCI: D-HEPTAPEPTIDE-1

CAS Number
Not publicly identified; supplier-specific CAS likely exists but not in open cosmetic references
Function
Bioactive cosmetic peptide with anti-ageing and skin-conditioning properties; signaling to upregulate repair and extracellular matrix components
Safety Rating
MODERATE

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status permitted
๐Ÿ‡บ๐Ÿ‡ธ US Status permitted
US Notes Not specifically restricted; used under general safety provisions; pre-market approval not required, but manufacturer must hold safety substantiation

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
not established
Dermal Absorption
moderate
Sensitization
low

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

Insufficient independent toxicological data; dependency on supplier studies for irritation, sensitization, genotoxicity, and systemic toxicity; restrict use concentrations and avoid high-exposure populations until robust data are available

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Concern Level: Moderate

Regulatory Flags

potential-allergen

Frequently Asked Questions

Is D-Heptapeptide-1 safe in cosmetics?

Insufficient independent toxicological data; dependency on supplier studies for irritation, sensitization, genotoxicity, and systemic toxicity; restrict use concentrations and avoid high-exposure populations until robust data are available The EU classifies D-Heptapeptide-1 as "permitted". Safety rating: MODERATE.

Is D-Heptapeptide-1 allowed in the EU?

D-Heptapeptide-1 EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does D-Heptapeptide-1 do in cosmetics?

D-Heptapeptide-1 functions as: Bioactive cosmetic peptide with anti-ageing and skin-conditioning properties; signaling to upregulate repair and extracellular matrix components. It is classified as a cosmetic ingredient in our database. CAS number: Not publicly identified; supplier-specific CAS likely exists but not in open cosmetic references.

What is the Margin of Safety for D-Heptapeptide-1?

not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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