NOAEL Studies
Cosmetic Ingredient
Decanal NOAEL Studies
INCI: DECANAL
CAS: 112-31-2
Raw No Observed Adverse Effect Level endpoint records grouped by source. This page does not render calculated Margin of Safety values.
ECHA_REACH_reach_study_results_dossiers_23-05-2023.zip 9 endpoints
| Source | Endpoint Type | Value | Unit | Species | Route | Duration | Study Type | Reference |
|---|---|---|---|---|---|---|---|---|
| ECHA_REACH_reach_study_results_dossiers_23-05-2023.zip | LOAEL | 1500 | mg/kg bw/day | rat | oral: gavage | - | one-generation reproductive toxicity | dossier=42781653-0df5-4bdf-899c-6b3f824e4318.i6z; document=aa3e557a-5409-4b66-a3fa-c305e26eee6a_42781653-0df5-4bdf-899c-6b3f824e4318.i6d; document_key=aa3e557a-5409-4b66-a3fa-c305e26eee6a/42781653-0df5-4bdf-899c-6b3f824e4318; document_subtype=ToxicityReproduction; literature=Name=Unnamed; ReferenceYear=1990; ReportDate=1990-01-01; basis=mortality; key_result=true; entry_uuid=cffa889f-a93d-4952-a86c-17a08c603bb2 |
| ECHA_REACH_reach_study_results_dossiers_23-05-2023.zip | LOAEL | 1500 | mg/kg bw/day | rat | oral: gavage | - | one-generation reproductive toxicity | dossier=42781653-0df5-4bdf-899c-6b3f824e4318.i6z; document=aa3e557a-5409-4b66-a3fa-c305e26eee6a_42781653-0df5-4bdf-899c-6b3f824e4318.i6d; document_key=aa3e557a-5409-4b66-a3fa-c305e26eee6a/42781653-0df5-4bdf-899c-6b3f824e4318; document_subtype=ToxicityReproduction; literature=Name=Unnamed; ReferenceYear=1990; ReportDate=1990-01-01; basis=mortality; key_result=true; entry_uuid=cffa889f-a93d-4952-a86c-17a08c603bb2 |
| ECHA_REACH_reach_study_results_dossiers_23-05-2023.zip | LOAEL | 1500 | mg/kg bw/day | rat | oral: gavage | - | one-generation reproductive toxicity | dossier=42781653-0df5-4bdf-899c-6b3f824e4318.i6z; document=aa3e557a-5409-4b66-a3fa-c305e26eee6a_42781653-0df5-4bdf-899c-6b3f824e4318.i6d; document_key=aa3e557a-5409-4b66-a3fa-c305e26eee6a/42781653-0df5-4bdf-899c-6b3f824e4318; document_subtype=ToxicityReproduction; literature=Name=Unnamed; ReferenceYear=1990; ReportDate=1990-01-01; basis=mortality; key_result=true; entry_uuid=cffa889f-a93d-4952-a86c-17a08c603bb2 |
| ECHA_REACH_reach_study_results_dossiers_23-05-2023.zip | NOAEL | 300 | mg/kg bw/day | rat | oral: gavage | - | one-generation reproductive toxicity | dossier=42781653-0df5-4bdf-899c-6b3f824e4318.i6z; document=aa3e557a-5409-4b66-a3fa-c305e26eee6a_42781653-0df5-4bdf-899c-6b3f824e4318.i6d; document_key=aa3e557a-5409-4b66-a3fa-c305e26eee6a/42781653-0df5-4bdf-899c-6b3f824e4318; document_subtype=ToxicityReproduction; literature=Name=Unnamed; ReferenceYear=1990; ReportDate=1990-01-01; basis=mortality; key_result=true; entry_uuid=9f7781b5-d235-4c6f-bee5-85bb4d09cd46 |
| ECHA_REACH_reach_study_results_dossiers_23-05-2023.zip | NOAEL | 200 | mg/kg bw/day | rat | oral: gavage | - | one-generation reproductive toxicity | dossier=42781653-0df5-4bdf-899c-6b3f824e4318.i6z; document=aa3e557a-5409-4b66-a3fa-c305e26eee6a_42781653-0df5-4bdf-899c-6b3f824e4318.i6d; document_key=aa3e557a-5409-4b66-a3fa-c305e26eee6a/42781653-0df5-4bdf-899c-6b3f824e4318; document_subtype=ToxicityReproduction; literature=Name=Unnamed; ReferenceYear=1990; ReportDate=1990-01-01; basis=organ weights and organ / body weight ratios; key_result=true; entry_uuid=1370fb0b-b239-4260-a35c-917957a8381b |
| ECHA_REACH_reach_study_results_dossiers_23-05-2023.zip | NOAEL | 300 | mg/kg bw/day | rat | oral: gavage | - | one-generation reproductive toxicity | dossier=42781653-0df5-4bdf-899c-6b3f824e4318.i6z; document=aa3e557a-5409-4b66-a3fa-c305e26eee6a_42781653-0df5-4bdf-899c-6b3f824e4318.i6d; document_key=aa3e557a-5409-4b66-a3fa-c305e26eee6a/42781653-0df5-4bdf-899c-6b3f824e4318; document_subtype=ToxicityReproduction; literature=Name=Unnamed; ReferenceYear=1990; ReportDate=1990-01-01; basis=mortality; key_result=true; entry_uuid=9f7781b5-d235-4c6f-bee5-85bb4d09cd46 |
| ECHA_REACH_reach_study_results_dossiers_23-05-2023.zip | NOAEL | 200 | mg/kg bw/day | rat | oral: gavage | - | one-generation reproductive toxicity | dossier=42781653-0df5-4bdf-899c-6b3f824e4318.i6z; document=aa3e557a-5409-4b66-a3fa-c305e26eee6a_42781653-0df5-4bdf-899c-6b3f824e4318.i6d; document_key=aa3e557a-5409-4b66-a3fa-c305e26eee6a/42781653-0df5-4bdf-899c-6b3f824e4318; document_subtype=ToxicityReproduction; literature=Name=Unnamed; ReferenceYear=1990; ReportDate=1990-01-01; basis=organ weights and organ / body weight ratios; key_result=true; entry_uuid=1370fb0b-b239-4260-a35c-917957a8381b |
| ECHA_REACH_reach_study_results_dossiers_23-05-2023.zip | NOAEL | 300 | mg/kg bw/day | rat | oral: gavage | - | one-generation reproductive toxicity | dossier=42781653-0df5-4bdf-899c-6b3f824e4318.i6z; document=aa3e557a-5409-4b66-a3fa-c305e26eee6a_42781653-0df5-4bdf-899c-6b3f824e4318.i6d; document_key=aa3e557a-5409-4b66-a3fa-c305e26eee6a/42781653-0df5-4bdf-899c-6b3f824e4318; document_subtype=ToxicityReproduction; literature=Name=Unnamed; ReferenceYear=1990; ReportDate=1990-01-01; basis=mortality; key_result=true; entry_uuid=9f7781b5-d235-4c6f-bee5-85bb4d09cd46 |
| ECHA_REACH_reach_study_results_dossiers_23-05-2023.zip | NOAEL | 200 | mg/kg bw/day | rat | oral: gavage | - | one-generation reproductive toxicity | dossier=42781653-0df5-4bdf-899c-6b3f824e4318.i6z; document=aa3e557a-5409-4b66-a3fa-c305e26eee6a_42781653-0df5-4bdf-899c-6b3f824e4318.i6d; document_key=aa3e557a-5409-4b66-a3fa-c305e26eee6a/42781653-0df5-4bdf-899c-6b3f824e4318; document_subtype=ToxicityReproduction; literature=Name=Unnamed; ReferenceYear=1990; ReportDate=1990-01-01; basis=organ weights and organ / body weight ratios; key_result=true; entry_uuid=1370fb0b-b239-4260-a35c-917957a8381b |
NTP_ICE_acute_oral 1 endpoint
| Source | Endpoint Type | Value | Unit | Species | Route | Duration | Study Type | Reference |
|---|---|---|---|---|---|---|---|---|
| NTP_ICE_acute_oral | LD50 | =3730 | mg/kg bw | Rat | oral | acute | Rat Acute Oral Toxicity | NLM Hazardous Substances Data Bank (undated); record_id=acute_oral_1176; row=7044; data_type=In Vivo; mixture=Chemical; chemical_name=Decanal; preferred_name=Decanal; dtxsid=DTXSID4021553; url=https://pubchem.ncbi.nlm.nih.gov/; url_comptox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID4021553; source_file=acute_oral.xlsx |
NTP_ICE_endocrine 1 endpoint
| Source | Endpoint Type | Value | Unit | Species | Route | Duration | Study Type | Reference |
|---|---|---|---|---|---|---|---|---|
| NTP_ICE_endocrine | Model Score | 0 | unitless | - | - | - | ARPathway2016; AR Pathway Model, Antagonist | sheet=Integrated_approaches; excel_row=7416; RecordID=ARPathway2016_603; DatasetName=ARPathway2016; DTXSID=DTXSID4021553; Assay=AR Pathway Model, Antagonist; Endpoint=Model Score; Response=0; Response_Unit=Unitless; URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID4021553 |
ToxValDB_ECHA_IUCLID 3 endpoints
| Source | Endpoint Type | Value | Unit | Species | Route | Duration | Study Type | Reference |
|---|---|---|---|---|---|---|---|---|
| ToxValDB_ECHA_IUCLID | LOAEL | =1500 | mg/kg bw/day | Rat | oral | - | reproduction developmental | QUALITY=2 (reliable with restrictions); STORED_SOURCE_RECORD=https://clowder.edap-cluster.com/files/669eaa64e4b0a7c65d1b59f9; RECORD_SOURCE_LEVEL=Extraction document; SOURCE_URL=https://echa.europa.eu/; SUBSOURCE_URL=https://echa.europa.eu/registration-dossier/-/registered-dossier/13619/7/9/2?documentUUID=42781653-0df5-4bdf-899c-6b3f824e4318; YEAR=1964; ORIGINAL_YEAR=1964; TOXICOLOGICAL_EFFECT=P0: clinical signs; TOXICOLOGICAL_EFFECT_CATEGORY=clinical signs; STUDY_GROUP=ECHA IUCLID_dup_Toxicity Reproduction_15855070_15855115_15855552_15855634_15855959_15855997_15856355_15856409:F:P0-; QC_CATEGORY=Programmatically extracted from structured data source; Source overall passed QC, but this record was not manually checked; QC_STATUS=not determined; SOURCE_HASH=ToxValhc_54c0a4514ff1425c41b88786be683527 |
| ToxValDB_ECHA_IUCLID | NOAEL | =300 | mg/kg bw/day | Rat | oral | - | reproduction developmental | QUALITY=2 (reliable with restrictions); STORED_SOURCE_RECORD=https://clowder.edap-cluster.com/files/669eaa64e4b0a7c65d1b59f9; RECORD_SOURCE_LEVEL=Extraction document; SOURCE_URL=https://echa.europa.eu/; SUBSOURCE_URL=https://echa.europa.eu/registration-dossier/-/registered-dossier/13619/7/9/2?documentUUID=42781653-0df5-4bdf-899c-6b3f824e4318; YEAR=1964; ORIGINAL_YEAR=1964; TOXICOLOGICAL_EFFECT=P0: clinical signs; TOXICOLOGICAL_EFFECT_CATEGORY=clinical signs; STUDY_GROUP=ECHA IUCLID_dup_Toxicity Reproduction_15855070_15855115_15855552_15855634_15855959_15855997_15856355_15856409:F:P0-; QC_CATEGORY=Programmatically extracted from structured data source; Source overall passed QC, but this record was not manually checked; QC_STATUS=not determined; SOURCE_HASH=ToxValhc_0f5e1232e18edd6df88fb7482facedd4 |
| ToxValDB_ECHA_IUCLID | NOAEL | =200 | mg/kg bw/day | Rat | oral | - | reproduction developmental | QUALITY=2 (reliable with restrictions); STORED_SOURCE_RECORD=https://clowder.edap-cluster.com/files/669eaa64e4b0a7c65d1b59fb; RECORD_SOURCE_LEVEL=Extraction document; SOURCE_URL=https://echa.europa.eu/; SUBSOURCE_URL=https://echa.europa.eu/registration-dossier/-/registered-dossier/13619/7/9/2?documentUUID=42781653-0df5-4bdf-899c-6b3f824e4318; YEAR=1964; ORIGINAL_YEAR=1964; TOXICOLOGICAL_EFFECT=F1: organ weights and organ / body weight ratios; TOXICOLOGICAL_EFFECT_CATEGORY=organ weight; STUDY_GROUP=ECHA IUCLID_dup_Toxicity Reproduction_15858936_15859002_15859564_15859656:M/F:F1-; QC_CATEGORY=Programmatically extracted from structured data source; Source overall passed QC, but this record was not manually checked; QC_STATUS=not determined; SOURCE_HASH=ToxValhc_724de2d548d7565af7b9045498a021b2 |
ToxValDB_GESTIS_DNEL 2 endpoints
| Source | Endpoint Type | Value | Unit | Species | Route | Duration | Study Type | Reference |
|---|---|---|---|---|---|---|---|---|
| ToxValDB_GESTIS_DNEL | DNEL local | =62.14 | mg/m3 | Human | inhalation | - | Toxicity Value | STORED_SOURCE_RECORD=https://clowder.edap-cluster.com/files/6543dd69e4b045b9ff7cd87e; RECORD_SOURCE_LEVEL=Extraction document; SOURCE_URL=https://www.dguv.de/ifa/gestis/gestis-dnel-liste/index-2.jsp; STUDY_GROUP=GESTIS DNEL_dup_-_15630928_15630929:-:--; QC_CATEGORY=Programmatically extracted from structured data source; Source overall passed QC, but this record was not manually checked; QC_STATUS=not determined; SOURCE_HASH=ToxValhc_baa5f6fe74061251e01b05d7a3b95094 |
| ToxValDB_GESTIS_DNEL | DNEL systemic | =24.86 | mg/m3 | Human | inhalation | - | Toxicity Value | STORED_SOURCE_RECORD=https://clowder.edap-cluster.com/files/6543dd69e4b045b9ff7cd87e; RECORD_SOURCE_LEVEL=Extraction document; SOURCE_URL=https://www.dguv.de/ifa/gestis/gestis-dnel-liste/index-2.jsp; STUDY_GROUP=GESTIS DNEL_dup_-_15630928_15630929:-:--; QC_CATEGORY=Programmatically extracted from structured data source; Source overall passed QC, but this record was not manually checked; QC_STATUS=not determined; SOURCE_HASH=ToxValhc_eca4dce949ae164812f0a1d454d1ce21 |
openFDA substances 4 endpoints
| Source | Endpoint Type | Value | Unit | Species | Route | Duration | Study Type | Reference |
|---|---|---|---|---|---|---|---|---|
| openFDA substances | FDA UNII substance identifier | 31Z90Q7KQJ | UNII | - | - | - | chemical | {"approval_status":null,"molecular_formula":"C10H20O","source_table":"substance_identifiers_fda","substance_class":"chemical","unii_code":"31Z90Q7KQJ"} |
| openFDA substances | FDA UNII substance identifier | 31Z90Q7KQJ | UNII | - | - | - | chemical | {"approval_status":null,"molecular_formula":"C10H20O","source_table":"substance_identifiers_fda","substance_class":"chemical","unii_code":"31Z90Q7KQJ"} |
| openFDA substances | FDA UNII substance identifier | 31Z90Q7KQJ | UNII | - | - | - | chemical | {"approval_status":null,"molecular_formula":"C10H20O","source_table":"substance_identifiers_fda","substance_class":"chemical","unii_code":"31Z90Q7KQJ"} |
| openFDA substances | FDA UNII substance identifier | 31Z90Q7KQJ | UNII | - | - | - | chemical | {"approval_status":null,"molecular_formula":"C10H20O","source_table":"substance_identifiers_fda","substance_class":"chemical","unii_code":"31Z90Q7KQJ"} |