Regulatory Status
For full compliance data across 55 jurisdictions, use the Substance Compliance tool.
Safety Data
Calculate MoS for your specific formulation with the MoS Calculator.
Toxicological Studies
10 study endpoints found for Decylamine Oxide. NOAEL (No Observed Adverse Effect Level) values are used to calculate the Margin of Safety per SCCS methodology.
| Endpoint | Value | Route | Species | Study Type | Source |
|---|---|---|---|---|---|
| NOAEL | 0.1 mg/kg bw/day | oral | rat | oral | REACH |
| LOEL | 2 other | dermal | code:3543 | dermal | REACH |
| NOAEL | 0.1 mg/kg bw/day | oral | rat | oral | REACH |
| LOEL | 0.27 other | dermal | code:3543 | dermal | REACH |
| NOAEL | 0.1 mg/kg bw/day | oral | - | oral | REACH |
| NOAEL | 40 mg/kg bw/day | oral | rat | oral | REACH |
| NOAEL | 40 mg/kg bw/day | oral | rat | oral | REACH |
| NOAEL | 0.1 mg/kg bw/day | oral | rabbit | oral | REACH |
| LOEL | 0.25 other | oral | rat | oral | REACH |
| NOAEL | 0.1 mg/kg bw/day | oral | rat | oral | REACH |
Expert Verdict
Potential irritant at higher concentrations (surfactant class). Monitor free amine impurities (dimethyldecylamine), which increase sensitization risk. pH-dependent behavior — more cationic at low pH, increasing skin interaction. Best suited for rinse-off applications.
Regulatory Flags
Frequently Asked Questions
Is Decylamine Oxide safe in cosmetics?
Potential irritant at higher concentrations (surfactant class). Monitor free amine impurities (dimethyldecylamine), which increase sensitization risk. pH-dependent behavior — more cationic at low pH, increasing skin interaction. Best suited for rinse-off applications. The EU classifies Decylamine Oxide as "permitted". Safety rating: MODERATE. 10 toxicological study endpoint(s) are available in our database.
Is Decylamine Oxide allowed in the EU?
Decylamine Oxide EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.
What does Decylamine Oxide do in cosmetics?
Decylamine Oxide functions as: Antistatic, cleansing, foam boosting (surfactant). It is classified as a cosmetic ingredient in our database. CAS number: 2605-79-0.
What is the Margin of Safety for Decylamine Oxide?
not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.
What is the NOAEL for Decylamine Oxide?
The NOAEL (No Observed Adverse Effect Level) for Decylamine Oxide is 0.1 mg/kg bw/day based on a oral study via oral route in rat. A total of 10 study endpoints are available. Source: REACH.
Compliance Tools
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Related Ingredients
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