NOAEL Studies Cosmetic Ingredient

Deoxyribonuclease NOAEL Studies

INCI: DEOXYRIBONUCLEASE

CAS: 9003-98-9

Raw No Observed Adverse Effect Level endpoint records grouped by source. This page does not render calculated Margin of Safety values.

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ToxValDB_ECHA_IUCLID 2 endpoints
Source Endpoint Type Value Unit Species Route Duration Study Type Reference
ToxValDB_ECHA_IUCLID NOAEL =1012.8 mg/kg bw/day Rat oral subchronic; 90 days subchronic QUALITY=1 (reliable without restriction); STORED_SOURCE_RECORD=https://clowder.edap-cluster.com/files/669eaf51e4b0a7c65d1cd72a; RECORD_SOURCE_LEVEL=Extraction document; SOURCE_URL=https://echa.europa.eu/; SUBSOURCE_URL=https://echa.europa.eu/registration-dossier/-/registered-dossier/22253/7/6/2?documentUUID=2eb801e9-fbb4-4592-875f-d2a06b3db4fc; YEAR=2016; ORIGINAL_YEAR=2016; STUDY_GROUP=ECHA IUCLID:15835211:M/F:--; QC_CATEGORY=Programmatically extracted from structured data source; Source overall passed QC, but this record was not manually checked; QC_STATUS=not determined; SOURCE_HASH=ToxValhc_c4876e3f025ec60ea15c9071bfe576b0
ToxValDB_ECHA_IUCLID NOAEL >=1184.1 mg/kg bw/day Rat oral short-term; 28 days short-term QUALITY=1 (reliable without restriction); STORED_SOURCE_RECORD=https://clowder.edap-cluster.com/files/669eaf51e4b0a7c65d1cd732; RECORD_SOURCE_LEVEL=Extraction document; SOURCE_URL=https://echa.europa.eu/; SUBSOURCE_URL=https://echa.europa.eu/registration-dossier/-/registered-dossier/22253/7/6/2?documentUUID=2eb801e9-fbb4-4592-875f-d2a06b3db4fc; YEAR=2016; ORIGINAL_YEAR=2016; STUDY_GROUP=ECHA IUCLID:15836666:M/F:--; QC_CATEGORY=Programmatically extracted from structured data source; Source overall passed QC, but this record was not manually checked; QC_STATUS=not determined; SOURCE_HASH=ToxValhc_4caea2109fbac3b18c28fea2e67adce3
openFDA substances 8 endpoints
Source Endpoint Type Value Unit Species Route Duration Study Type Reference
openFDA substances FDA UNII substance identifier 0BE71HM000 UNII - - - protein {"approval_status":null,"molecular_formula":null,"source_table":"substance_identifiers_fda","substance_class":"protein","unii_code":"0BE71HM000"}
openFDA substances FDA UNII substance identifier 0BE71HM000 UNII - - - protein {"approval_status":null,"molecular_formula":null,"source_table":"substance_identifiers_fda","substance_class":"protein","unii_code":"0BE71HM000"}
openFDA substances FDA UNII substance identifier 0BE71HM000 UNII - - - protein {"approval_status":null,"molecular_formula":null,"source_table":"substance_identifiers_fda","substance_class":"protein","unii_code":"0BE71HM000"}
openFDA substances FDA UNII substance identifier 0BE71HM000 UNII - - - protein {"approval_status":null,"molecular_formula":null,"source_table":"substance_identifiers_fda","substance_class":"protein","unii_code":"0BE71HM000"}
openFDA substances FDA UNII substance identifier concept identifier - - - concept {"approval_status":null,"molecular_formula":null,"source_table":"substance_identifiers_fda","substance_class":"concept","unii_code":null}
openFDA substances FDA UNII substance identifier concept identifier - - - concept {"approval_status":null,"molecular_formula":null,"source_table":"substance_identifiers_fda","substance_class":"concept","unii_code":null}
openFDA substances FDA UNII substance identifier concept identifier - - - concept {"approval_status":null,"molecular_formula":null,"source_table":"substance_identifiers_fda","substance_class":"concept","unii_code":null}
openFDA substances FDA UNII substance identifier concept identifier - - - concept {"approval_status":null,"molecular_formula":null,"source_table":"substance_identifiers_fda","substance_class":"concept","unii_code":null}