Diacetylresveratryl Thioctate

INCI: DIACETYLRESVERATRYL THIOCTATE

CAS Number
1082892-39-4
Function
Antioxidant, skin conditioning (resveratrol + lipoic acid prodrug)
Safety Rating
MODERATE

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status prohibited
๐Ÿ‡บ๐Ÿ‡ธ US Status restricted
US Notes Permitted โ€” not specifically restricted

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
not established
Dermal Absorption
high
Sensitization
low

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

Novel synthetic prodrug combining resveratrol and ฮฑ-lipoic acid moieties with very limited published toxicological data. Enhanced skin penetration design increases systemic exposure concern; requires in vitro dermal absorption study, HRIPT, and genotoxicity panel before CPSR completion.

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Concern Level: High

Frequently Asked Questions

Is Diacetylresveratryl Thioctate safe in cosmetics?

Novel synthetic prodrug combining resveratrol and ฮฑ-lipoic acid moieties with very limited published toxicological data. Enhanced skin penetration design increases systemic exposure concern; requires in vitro dermal absorption study, HRIPT, and genotoxicity panel before CPSR completion. The EU classifies Diacetylresveratryl Thioctate as "prohibited". Safety rating: MODERATE.

Is Diacetylresveratryl Thioctate allowed in the EU?

Diacetylresveratryl Thioctate EU regulatory status: prohibited. This is based on EU Regulation 1223/2009 and its amendments.

What does Diacetylresveratryl Thioctate do in cosmetics?

Diacetylresveratryl Thioctate functions as: Antioxidant, skin conditioning (resveratrol + lipoic acid prodrug). It is classified as a cosmetic ingredient in our database. CAS number: 1082892-39-4.

What is the Margin of Safety for Diacetylresveratryl Thioctate?

not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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