Good Cosmetic Ingredient NOAEL Data

Dibenzylidene Sorbitol

INCI: DIBENZYLIDENE SORBITOL

CAS Number
32647-67-9
Function
Viscosity controlling gellant for stick formulations
Safety Rating
GOOD

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status permitted
๐Ÿ‡บ๐Ÿ‡ธ US Status permitted
US Notes Permitted, not prohibited under 21 CFR; also used in food-contact applications

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
adequate
Dermal Absorption
negligible
Sensitization
low

Calculate MoS for your specific formulation with the MoS Calculator.

Toxicological Studies

4 study endpoints found for Dibenzylidene Sorbitol. NOAEL (No Observed Adverse Effect Level) values are used to calculate the Margin of Safety per SCCS methodology.

Endpoint Value Route Species Study Type Source
NOEL 200 mg/kg bw/day oral rat oral REACH
NOAEL 2000 other oral rat oral REACH
NOAEL 3200 other oral mouse oral REACH
NOEL 200 mg/kg bw/day oral - oral REACH

Expert Verdict

Unstable in acidic media and hydrolyzes; avoid in low-pH formulations with water and ensure supplier confirms residual benzaldehyde levels below limits.

โš ๏ธ
Concern Level: Low

Frequently Asked Questions

Is Dibenzylidene Sorbitol safe in cosmetics?

Unstable in acidic media and hydrolyzes; avoid in low-pH formulations with water and ensure supplier confirms residual benzaldehyde levels below limits. The EU classifies Dibenzylidene Sorbitol as "permitted". Safety rating: GOOD. 4 toxicological study endpoint(s) are available in our database.

Is Dibenzylidene Sorbitol allowed in the EU?

Dibenzylidene Sorbitol EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Dibenzylidene Sorbitol do in cosmetics?

Dibenzylidene Sorbitol functions as: Viscosity controlling gellant for stick formulations. It is classified as a cosmetic ingredient in our database. CAS number: 32647-67-9.

What is the Margin of Safety for Dibenzylidene Sorbitol?

adequate The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

What is the NOAEL for Dibenzylidene Sorbitol?

The NOAEL (No Observed Adverse Effect Level) for Dibenzylidene Sorbitol is 200 mg/kg bw/day based on a oral study via oral route in rat. A total of 4 study endpoints are available. Source: REACH.

๐Ÿ“ฑ

Is Dibenzylidene Sorbitol in Your Products?

Scan any product label with Piro โ€” our free ingredient scanner. Point your camera at the ingredients list and get instant safety scores for every ingredient.

Try Piro Free โ†’

Analyze Your Full Ingredient List

Paste any INCI list into the Decoder for instant safety analysis, or calculate the Margin of Safety for Dibenzylidene Sorbitol in your formulation.