NOAEL Studies Cosmetic Ingredient

Dibutyl Maleate NOAEL Studies

INCI: DIBUTYL MALEATE

CAS: 105-76-0

Raw No Observed Adverse Effect Level endpoint records grouped by source. This page does not render calculated Margin of Safety values.

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NTP_ICE_acute_oral 1 endpoint
Source Endpoint Type Value Unit Species Route Duration Study Type Reference
NTP_ICE_acute_oral LD50 =3700 mg/kg bw Rat oral acute Rat Acute Oral Toxicity NLM ChemIDplus TEST (undated); record_id=acute_oral_491; row=5876; data_type=In Vivo; mixture=Chemical; chemical_name=Dibutyl maleate; preferred_name=Dibutyl maleate; dtxsid=DTXSID3026724; url=https://chem.nlm.nih.gov/chemidplus/; url_comptox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID3026724; source_file=acute_oral.xlsx
ToxValDB_GESTIS_DNEL 1 endpoint
Source Endpoint Type Value Unit Species Route Duration Study Type Reference
ToxValDB_GESTIS_DNEL DNEL local =5.28 mg/m3 Human inhalation - Toxicity Value STORED_SOURCE_RECORD=https://clowder.edap-cluster.com/files/6543dd69e4b045b9ff7cd87e; RECORD_SOURCE_LEVEL=Extraction document; SOURCE_URL=https://www.dguv.de/ifa/gestis/gestis-dnel-liste/index-2.jsp; STUDY_GROUP=GESTIS DNEL_dup_-_15631040_15631041:-:--; QC_CATEGORY=Programmatically extracted from structured data source; Source overall passed QC, but this record was not manually checked; QC_STATUS=not determined; SOURCE_HASH=ToxValhc_6d75e6eb67c4de212943b28661628f1e
openFDA substances 4 endpoints
Source Endpoint Type Value Unit Species Route Duration Study Type Reference
openFDA substances FDA UNII substance identifier 4X371TMK9K UNII - - - chemical {"approval_status":null,"molecular_formula":"C12H20O4","source_table":"substance_identifiers_fda","substance_class":"chemical","unii_code":"4X371TMK9K"}
openFDA substances FDA UNII substance identifier 4X371TMK9K UNII - - - chemical {"approval_status":null,"molecular_formula":"C12H20O4","source_table":"substance_identifiers_fda","substance_class":"chemical","unii_code":"4X371TMK9K"}
openFDA substances FDA UNII substance identifier 4X371TMK9K UNII - - - chemical {"approval_status":null,"molecular_formula":"C12H20O4","source_table":"substance_identifiers_fda","substance_class":"chemical","unii_code":"4X371TMK9K"}
openFDA substances FDA UNII substance identifier 4X371TMK9K UNII - - - chemical {"approval_status":null,"molecular_formula":"C12H20O4","source_table":"substance_identifiers_fda","substance_class":"chemical","unii_code":"4X371TMK9K"}