Is Dihydroxyindoline HBr safe in cosmetics?
Dihydroxyindoline HBr has a safety rating of "GOOD" in our database. EU status: prohibited. US status: permitted.
Good
Cosmetic Ingredient
Dihydroxyindoline HBr
INCI: DIHYDROXYINDOLINE HBR
Dihydroxyindoline HBr (CAS 138937-28-7 (EINECS 421-170-6)) is a cosmetic cosmetic ingredient functioning as Hair dyeing — hydrobromide salt of dihydroxyindoline for non-oxidative hair dye. EU Regulation 1223/2009 status: prohibited. Industrial safety data is also available in the chemical safety database.
View industrial chemical safety profile for CAS 138937-28-7 (EINECS 421-170-6) →
Auto-generated CPSR Part A draft with source citations
Function
Hair dyeing — hydrobromide salt of dihydroxyindoline for non-oxidative hair dye products
Safety Rating
GOOD
Regulatory Status
EU EU Status
prohibited
US US Status
permitted
US Notes
Permitted under coal-tar hair dye exemption; same regulatory pathway as free base
For full compliance data across multiple jurisdictions, use the Substance Compliance tool.
Safety Data
Margin of Safety, dermal absorption, and sensitization profile summaries for Dihydroxyindoline HBr.
Calculate MoS for your specific formulation with the MoS Calculator.
Additional Ingredient Properties
1 property record from structured ingredient metadata.
hair_dye
{"cas_number": "29539-03-5", "ingredient_class": "oxidative_dye_coupler", "chemical_class": "other", "molecular_weight_Da": "216.06", "color_result_on_hair": "Progressive brown/black", "shade_range": "brown", "primary_function": "coupler", "oxidative_dye_type": "coupler", "requires_developer": "no", "permanence": "semi_permanent", "oxidation_mechanism": "coupling", "hair_penetration_depth": "cutic…
Expert Verdict
Expert safety assessment and concern-level summary for Dihydroxyindoline HBr.
Frequently Asked Questions
Is Dihydroxyindoline HBr allowed in the EU?
Dihydroxyindoline HBr EU regulatory status: prohibited. This is based on EU Regulation 1223/2009 and its amendments.
What does Dihydroxyindoline HBr do in cosmetics?
Dihydroxyindoline HBr functions as: Hair dyeing — hydrobromide salt of dihydroxyindoline for non-oxidative hair dye products. It is classified as a cosmetic ingredient in our database. CAS number: 138937-28-7 (EINECS 421-170-6).
Compliance Tools
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Substance Compliance
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MoS Calculator
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Heavy Metal Limits
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