Regulatory Status
For full compliance data across 55 jurisdictions, use the Substance Compliance tool.
Safety Data
Calculate MoS for your specific formulation with the MoS Calculator.
Toxicological Studies
3 study endpoints found for Dimethyl 2,6-Naphthalate. NOAEL (No Observed Adverse Effect Level) values are used to calculate the Margin of Safety per SCCS methodology.
| Endpoint | Value | Route | Species | Study Type | Source |
|---|---|---|---|---|---|
| LOAEL | 2000 ppm | oral | rat | Subchronic | COSMOS_DB |
| NOEL | 3000 mg/kg bw/day | oral | rat | oral | REACH |
| NOAEL | 1000 mg/kg bw/day | oral | rat | oral | REACH |
Expert Verdict
Australian NICNAS assessment indicates it would not be classified as hazardous. SDS warns to avoid dust inhalation and prolonged skin contact. Primarily an industrial chemical (PEN plastic precursor); cosmetic use data is sparse. Residual monomer limits should be verified if used in cosmetics.
Frequently Asked Questions
Is Dimethyl 2,6-Naphthalate safe in cosmetics?
Australian NICNAS assessment indicates it would not be classified as hazardous. SDS warns to avoid dust inhalation and prolonged skin contact. Primarily an industrial chemical (PEN plastic precursor); cosmetic use data is sparse. Residual monomer limits should be verified if used in cosmetics. The EU classifies Dimethyl 2,6-Naphthalate as "prohibited". Safety rating: MODERATE. 3 toxicological study endpoint(s) are available in our database.
Is Dimethyl 2,6-Naphthalate allowed in the EU?
Dimethyl 2,6-Naphthalate EU regulatory status: prohibited. This is based on EU Regulation 1223/2009 and its amendments.
What does Dimethyl 2,6-Naphthalate do in cosmetics?
Dimethyl 2,6-Naphthalate functions as: Skin conditioning agent. It is classified as a cosmetic ingredient in our database. CAS number: 840-65-3.
What is the Margin of Safety for Dimethyl 2,6-Naphthalate?
not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.
What is the NOAEL for Dimethyl 2,6-Naphthalate?
The NOAEL (No Observed Adverse Effect Level) for Dimethyl 2,6-Naphthalate is 2000 ppm based on a Subchronic study via oral route in rat. A total of 3 study endpoints are available. Source: COSMOS_DB.
Compliance Tools
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Related Ingredients
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