Dimethyl Cystinate

INCI: DIMETHYL CYSTINATE

CAS Number
14545-08-5 (L-Cystine dimethyl ester) — *verify against your COSING listing*
Function
Hair conditioning (cystine derivative)
Safety Rating
MODERATE

Regulatory Status

🇪🇺 EU Status permitted
🇺🇸 US Status permitted
US Notes Permitted — no specific CFR prohibition; limited CIR data

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
not established
Dermal Absorption
low
Sensitization
low

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

Insufficient published toxicological data for a full CPSR evaluation; read-across from cystine/cysteine esters may be acceptable but must be justified

⚠️
Concern Level: Moderate

Frequently Asked Questions

Is Dimethyl Cystinate safe in cosmetics?

Insufficient published toxicological data for a full CPSR evaluation; read-across from cystine/cysteine esters may be acceptable but must be justified The EU classifies Dimethyl Cystinate as "permitted". Safety rating: MODERATE.

Is Dimethyl Cystinate allowed in the EU?

Dimethyl Cystinate EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Dimethyl Cystinate do in cosmetics?

Dimethyl Cystinate functions as: Hair conditioning (cystine derivative). It is classified as a cosmetic ingredient in our database. CAS number: 14545-08-5 (L-Cystine dimethyl ester) — *verify against your COSING listing*.

What is the Margin of Safety for Dimethyl Cystinate?

not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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