Dimethyl Diacetyl Cystinate

INCI: DIMETHYL DIACETYL CYSTINATE

CAS Number
139612-43-4 (dl-form, COSING) ; 32381-28-5 (L-form, N,N′-Diacetyl-L-cystine dimethyl ester)
Function
Hair conditioning
Safety Rating
MODERATE

Regulatory Status

🇪🇺 EU Status permitted
🇺🇸 US Status permitted
US Notes Permitted — no CFR prohibition; not CIR-reviewed as individual ingredient

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
not established
Dermal Absorption
low
Sensitization
low

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

Primarily a research reagent with limited cosmetic-use toxicological data; read-across from N-acetylcysteine derivatives advisable.

⚠️
Concern Level: Moderate

Frequently Asked Questions

Is Dimethyl Diacetyl Cystinate safe in cosmetics?

Primarily a research reagent with limited cosmetic-use toxicological data; read-across from N-acetylcysteine derivatives advisable. The EU classifies Dimethyl Diacetyl Cystinate as "permitted". Safety rating: MODERATE.

Is Dimethyl Diacetyl Cystinate allowed in the EU?

Dimethyl Diacetyl Cystinate EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Dimethyl Diacetyl Cystinate do in cosmetics?

Dimethyl Diacetyl Cystinate functions as: Hair conditioning. It is classified as a cosmetic ingredient in our database. CAS number: 139612-43-4 (dl-form, COSING) ; 32381-28-5 (L-form, N,N′-Diacetyl-L-cystine dimethyl ester).

What is the Margin of Safety for Dimethyl Diacetyl Cystinate?

not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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