NOAEL Studies Cosmetic Ingredient

Dimethyl Stearamine NOAEL Studies

INCI: DIMETHYL STEARAMINE

CAS: 124-28-7

Raw No Observed Adverse Effect Level endpoint records grouped by source. This page does not render calculated Margin of Safety values.

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CIR Safety Assessment 1 endpoint
Source Endpoint Type Value Unit Species Route Duration Study Type Reference
CIR Safety Assessment NOAEL =50 mg/kg bw rat oral 14 days developmental toxicity 300; 3; 5, p.8
NTP ICE acute oral 2 endpoints
Source Endpoint Type Value Unit Species Route Duration Study Type Reference
NTP ICE acute oral LD50 =2116 mg/kg bw Rat oral acute Rat Acute Oral Toxicity OECD eChemPortal (undated); record_id=acute_oral_1912; row=7366; data_type=In Vivo; mixture=Chemical; chemical_name=N,N-Dimethyl-1-octadecanamine; preferred_name=N,N-Dimethyl-1-octadecanamine; dtxsid=DTXSID4027026; url=https://www.echemportal.org/echemportal/; url_comptox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID4027026; source_file=acute_oral.xlsx
NTP ICE acute oral LD50 =2118 mg/kg bw Rat oral acute Rat Acute Oral Toxicity OECD eChemPortal (undated); record_id=acute_oral_1913; row=7365; data_type=In Vivo; mixture=Chemical; chemical_name=N,N-Dimethyl-1-octadecanamine; preferred_name=N,N-Dimethyl-1-octadecanamine; dtxsid=DTXSID4027026; url=https://www.echemportal.org/echemportal/; url_comptox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID4027026; source_file=acute_oral.xlsx
ToxValDB GESTIS DNEL 1 endpoint
Source Endpoint Type Value Unit Species Route Duration Study Type Reference
ToxValDB GESTIS DNEL DNEL local =1 mg/m3 Human inhalation - Toxicity Value STORED_SOURCE_RECORD=https://clowder.edap-cluster.com/files/6543dd69e4b045b9ff7cd87e; RECORD_SOURCE_LEVEL=Extraction document; SOURCE_URL=https://www.dguv.de/ifa/gestis/gestis-dnel-liste/index-2.jsp; STUDY_GROUP=GESTIS DNEL_dup_-_15631301_15631302:-:--; QC_CATEGORY=Programmatically extracted from structured data source; Source overall passed QC, but this record was not manually checked; QC_STATUS=not determined; SOURCE_HASH=ToxValhc_c0622856bedacfdba346968c1c8cf1ac
openFDA substances 1 endpoint
Source Endpoint Type Value Unit Species Route Duration Study Type Reference
openFDA substances FDA UNII substance identifier 066975NG22 UNII - - - chemical -