NOAEL Studies Cosmetic Ingredient

Dimethylamino Methylpropanol (DMAMP) NOAEL Studies

INCI: DIMETHYLAMINO METHYLPROPANOL

CAS: 7005-47-2

Raw No Observed Adverse Effect Level endpoint records grouped by source. This page does not render calculated Margin of Safety values.

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ToxValDB_ECHA_IUCLID 3 endpoints
Source Endpoint Type Value Unit Species Route Duration Study Type Reference
ToxValDB_ECHA_IUCLID LOEL ~1000 mg/kg bw/day Rat oral - reproduction developmental QUALITY=2 (reliable with restrictions); STORED_SOURCE_RECORD=https://clowder.edap-cluster.com/files/669eab47e4b0a7c65d1b9936; RECORD_SOURCE_LEVEL=Extraction document; SOURCE_URL=https://echa.europa.eu/; SUBSOURCE_URL=https://echa.europa.eu/registration-dossier/-/registered-dossier/11939/7/9/2?documentUUID=d1d84aa4-6cc3-4447-aa41-e9628a50a1a8; YEAR=2012; ORIGINAL_YEAR=2012; STUDY_GROUP=ECHA IUCLID_dup_Toxicity Reproduction_15855560_15856361:F:P0-; QC_CATEGORY=Programmatically extracted from structured data source; Source overall passed QC, but this record was not manually checked; QC_STATUS=not determined; SOURCE_HASH=ToxValhc_aa15c6e31491d2d7657e44841e8f479a
ToxValDB_ECHA_IUCLID NOAEL =300 mg/kg bw/day Rat oral chronic; 92 days chronic QUALITY=1 (reliable without restriction); STORED_SOURCE_RECORD=https://clowder.edap-cluster.com/files/669eaecae4b0a7c65d1cb0d0; RECORD_SOURCE_LEVEL=Extraction document; SOURCE_URL=https://echa.europa.eu/; SUBSOURCE_URL=https://echa.europa.eu/registration-dossier/-/registered-dossier/11939/7/6/2?documentUUID=d1d84aa4-6cc3-4447-aa41-e9628a50a1a8; YEAR=2012; ORIGINAL_YEAR=2012; STUDY_GROUP=ECHA IUCLID:15835785:M/F:--; QC_CATEGORY=Programmatically extracted from structured data source; Source overall passed QC, but this record was not manually checked; QC_STATUS=not determined; SOURCE_HASH=ToxValhc_9ff6236eed0c762c9ec04d3f51593b1d
ToxValDB_ECHA_IUCLID NOEL =300 mg/kg bw/day Rat oral - developmental GUIDELINE=OECD Guideline 414 (Prenatal Developmental Toxicity Study); QUALITY=1 (reliable without restriction); STORED_SOURCE_RECORD=https://clowder.edap-cluster.com/files/669eac62e4b0a7c65d1beca7; RECORD_SOURCE_LEVEL=Extraction document; SOURCE_URL=https://echa.europa.eu/; SUBSOURCE_URL=https://echa.europa.eu/registration-dossier/-/registered-dossier/11939/7/9/3?documentUUID=d1d84aa4-6cc3-4447-aa41-e9628a50a1a8; YEAR=2012; ORIGINAL_YEAR=2012; STUDY_GROUP=ECHA IUCLID:15821221:-:-fetal; QC_CATEGORY=Programmatically extracted from structured data source; Source overall passed QC, but this record was not manually checked; QC_STATUS=not determined; SOURCE_HASH=ToxValhc_c14b116acce53b7c1f66581824845671
ToxValDB_GESTIS_DNEL 1 endpoint
Source Endpoint Type Value Unit Species Route Duration Study Type Reference
ToxValDB_GESTIS_DNEL DNEL systemic =52.9 mg/m3 Human inhalation - Toxicity Value STORED_SOURCE_RECORD=https://clowder.edap-cluster.com/files/6543dd69e4b045b9ff7cd87e; RECORD_SOURCE_LEVEL=Extraction document; SOURCE_URL=https://www.dguv.de/ifa/gestis/gestis-dnel-liste/index-2.jsp; STUDY_GROUP=GESTIS DNEL:15631338:-:--; QC_CATEGORY=Programmatically extracted from structured data source; Source overall passed QC, but this record was not manually checked; QC_STATUS=not determined; SOURCE_HASH=ToxValhc_00ef46fa489ee59892e919b8b4de7b6c
openFDA substances 4 endpoints
Source Endpoint Type Value Unit Species Route Duration Study Type Reference
openFDA substances FDA UNII substance identifier 6ZWG40UQ9E UNII - - - chemical {"approval_status":null,"molecular_formula":"C6H15NO","source_table":"substance_identifiers_fda","substance_class":"chemical","unii_code":"6ZWG40UQ9E"}
openFDA substances FDA UNII substance identifier 6ZWG40UQ9E UNII - - - chemical {"approval_status":null,"molecular_formula":"C6H15NO","source_table":"substance_identifiers_fda","substance_class":"chemical","unii_code":"6ZWG40UQ9E"}
openFDA substances FDA UNII substance identifier 6ZWG40UQ9E UNII - - - chemical {"approval_status":null,"molecular_formula":"C6H15NO","source_table":"substance_identifiers_fda","substance_class":"chemical","unii_code":"6ZWG40UQ9E"}
openFDA substances FDA UNII substance identifier 6ZWG40UQ9E UNII - - - chemical {"approval_status":null,"molecular_formula":"C6H15NO","source_table":"substance_identifiers_fda","substance_class":"chemical","unii_code":"6ZWG40UQ9E"}