Moderate Cosmetic Ingredient

Dipeptide-8 HCl

INCI: DIPEPTIDE-8 HCL (HYDROCHLORIDE SALT FORM OF DIPEPTIDE-8)

CAS Number
Not confirmed in publicly available sources.
Function
Same as Dipeptide-8 - skin conditioning, hydrating. The HCl salt form improves water solubility and formulation stability.
Safety Rating
MODERATE

Regulatory Status

🇪🇺 EU Status prohibited
🇺🇸 US Status permitted
US Notes Not specifically prohibited or restricted.

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
not established
Dermal Absorption
low
Sensitization
low

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

No unique concerns beyond the parent peptide. Salt forms generally do not introduce additional toxicity.. The hydrochloride salt typically offers improved stability in aqueous formulations compared to the free-base form.

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Concern Level: High

Frequently Asked Questions

Is Dipeptide-8 HCl safe in cosmetics?

No unique concerns beyond the parent peptide. Salt forms generally do not introduce additional toxicity.. The hydrochloride salt typically offers improved stability in aqueous formulations compared to the free-base form. The EU classifies Dipeptide-8 HCl as "prohibited". Safety rating: MODERATE.

Is Dipeptide-8 HCl allowed in the EU?

Dipeptide-8 HCl EU regulatory status: prohibited. This is based on EU Regulation 1223/2009 and its amendments.

What does Dipeptide-8 HCl do in cosmetics?

Dipeptide-8 HCl functions as: Same as Dipeptide-8 - skin conditioning, hydrating. The HCl salt form improves water solubility and formulation stability.. It is classified as a cosmetic ingredient in our database. CAS number: Not confirmed in publicly available sources..

What is the Margin of Safety for Dipeptide-8 HCl?

not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

Compliance Tools

Check Dipeptide-8 HCl compliance across multiple jurisdictions:

🔬
Ingredient Decoder
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82 Allergen Checker
Check for EU declarable fragrance allergens
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Substance Compliance
Check compliance across 55 jurisdictions
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MoS Calculator
Calculate Margin of Safety using SCCS methodology
 ⚗️
Heavy Metal Limits
Compare limits across jurisdictions

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