Regulatory Status
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Safety Data
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Expert Verdict
Callus culture extract with manufacturing consistency and standardization concerns; Diphylleia grayi may contain podophyllotoxin-related compounds (genus-level concern in Berberidaceae); requires compositional analysis and 48 h HRIPT minimum before CPSR submission
Regulatory Flags
Frequently Asked Questions
Is Diphylleia Grayi Callus Extract safe in cosmetics?
Callus culture extract with manufacturing consistency and standardization concerns; Diphylleia grayi may contain podophyllotoxin-related compounds (genus-level concern in Berberidaceae); requires compositional analysis and 48 h HRIPT minimum before CPSR submission The EU classifies Diphylleia Grayi Callus Extract as "restricted". Safety rating: MODERATE.
Is Diphylleia Grayi Callus Extract allowed in the EU?
Diphylleia Grayi Callus Extract EU regulatory status: restricted. This is based on EU Regulation 1223/2009 and its amendments.
What does Diphylleia Grayi Callus Extract do in cosmetics?
Diphylleia Grayi Callus Extract functions as: Astringent, skin conditioning. It is classified as a cosmetic ingredient in our database. CAS number: Not assigned.
What is the Margin of Safety for Diphylleia Grayi Callus Extract?
not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.
Compliance Tools
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Related Ingredients
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