Regulatory Status
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Safety Data
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Expert Verdict
Dipotassium glycyrrhizate is the preferred water-soluble salt form of glycyrrhizic acid for cosmetic formulation. Anti-inflammatory mechanism via phospholipase A2 inhibition is well-characterised. CIR concluded safe as used. Negligible dermal absorption confirmed — oral mineralocorticoid concerns from glycyrrhizic acid do not apply to topical cosmetic use. Standard anti-inflammatory, sensitive-skin soothing active. Unrestricted globally.
Regulatory Flags
Frequently Asked Questions
Is Dipotassium Glycyrrhizate safe in cosmetics?
Dipotassium glycyrrhizate is the preferred water-soluble salt form of glycyrrhizic acid for cosmetic formulation. Anti-inflammatory mechanism via phospholipase A2 inhibition is well-characterised. CIR concluded safe as used. Negligible dermal absorption confirmed — oral mineralocorticoid concerns from glycyrrhizic acid do not apply to topical cosmetic use. Standard anti-inflammatory, sensitive-skin soothing active. Unrestricted globally. The EU classifies Dipotassium Glycyrrhizate as "permitted". Safety rating: GOOD.
Is Dipotassium Glycyrrhizate allowed in the EU?
Dipotassium Glycyrrhizate EU regulatory status: permitted. Maximum allowed concentration: 6%. This is based on EU Regulation 1223/2009 and its amendments.
What does Dipotassium Glycyrrhizate do in cosmetics?
Dipotassium Glycyrrhizate functions as: Dipotassium salt of glycyrrhizic acid (triterpenoid saponin, Glycyrrhiza glabra). Water-soluble salt form preferred in cosmetic formulations. Anti-inflammatory via phospholipase A2 inhibition; surfactant; skin conditioning. Functionally equivalent to glycyrrhizic acid at equivalent molar doses. Widely used anti-inflammatory and soothing active in sensitive-skin, atopic, and anti-redness formulations.. It is classified as a Cosmetic Ingredient in our database. CAS number: 68797-35-3.
What is the Margin of Safety for Dipotassium Glycyrrhizate?
not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.
Compliance Tools
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Related Ingredients
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