Disodium Ascorbyl Sulfate

INCI: DISODIUM ASCORBYL SULFATE

CAS Number
53910-28-4
Function
Antioxidant
Safety Rating
MODERATE

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status permitted
๐Ÿ‡บ๐Ÿ‡ธ US Status permitted
US Notes No FDA restriction; not reviewed by CIR specifically; parent ascorbic acid class is GRAS as food additive (21 CFR 182.3013)

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
not established
Dermal Absorption
low
Sensitization
low

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

Vitamin C derivative with antioxidant and brightening function. Thin safety dossier with no SCCS opinion or specific CIR review; read-across from ascorbic acid class is plausible but must be formally justified in CPSR.

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Concern Level: Moderate

Regulatory Flags

antioxidant vitamin-c-derivative data-gap no-sccs-opinion no-cir-review brightening sulfate-ester cpsr-read-across-required

Frequently Asked Questions

Is Disodium Ascorbyl Sulfate safe in cosmetics?

Vitamin C derivative with antioxidant and brightening function. Thin safety dossier with no SCCS opinion or specific CIR review; read-across from ascorbic acid class is plausible but must be formally justified in CPSR. The EU classifies Disodium Ascorbyl Sulfate as "permitted". Safety rating: MODERATE.

Is Disodium Ascorbyl Sulfate allowed in the EU?

Disodium Ascorbyl Sulfate EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Disodium Ascorbyl Sulfate do in cosmetics?

Disodium Ascorbyl Sulfate functions as: Antioxidant. It is classified as a cosmetic ingredient in our database. CAS number: 53910-28-4.

What is the Margin of Safety for Disodium Ascorbyl Sulfate?

not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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