NOAEL Studies Cosmetic Ingredient

Disodium Fumarate NOAEL Studies

INCI: DISODIUM FUMARATE

CAS: 17013-01-3

Raw No Observed Adverse Effect Level endpoint records grouped by source. This page does not render calculated Margin of Safety values.

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CIR Safety Assessment 4 endpoints
Source Endpoint Type Value Unit Species Route Duration Study Type Reference
CIR Safety Assessment NOAEL =2080 mg/kg bw/day rabbit oral 28 days general toxicity {"citation":"0","dose":"320-2080 mg/kg bw","effect":"no deaths","page":8,"pdf":"FR464.pdf","row_type":"noael_study","study_id":"Locke_1942_Disodium_Fumarate_Oral"}
CIR Safety Assessment NOAEL =2080 mg/kg bw/day rabbit oral 28 days general toxicity {"citation":"0","dose":"320-2080 mg/kg bw","effect":"no deaths","page":8,"pdf":"FR464.pdf","row_type":"noael_study","study_id":"Locke_1942_Disodium_Fumarate_Oral"}
CIR Safety Assessment NOAEL =2080 mg/kg bw/day rabbit oral 28 days general toxicity {"citation":"0","dose":"320-2080 mg/kg bw","effect":"no deaths","page":8,"pdf":"FR464.pdf","row_type":"noael_study","study_id":"Locke_1942_Disodium_Fumarate_Oral"}
CIR Safety Assessment NOAEL =2080 mg/kg bw/day rabbit oral 28 days general toxicity {"citation":"0","dose":"320-2080 mg/kg bw","effect":"no deaths","page":8,"pdf":"FR464.pdf","row_type":"noael_study","study_id":"Locke_1942_Disodium_Fumarate_Oral"}
openFDA substances 3 endpoints
Source Endpoint Type Value Unit Species Route Duration Study Type Reference
openFDA substances FDA UNII substance identifier 0578QTK490 UNII - - - chemical {"approval_status":null,"molecular_formula":"C4H2O4.2Na","source_table":"substance_identifiers_fda","substance_class":"chemical","unii_code":"0578QTK490"}
openFDA substances FDA UNII substance identifier 0578QTK490 UNII - - - chemical {"approval_status":null,"molecular_formula":"C4H2O4.2Na","source_table":"substance_identifiers_fda","substance_class":"chemical","unii_code":"0578QTK490"}
openFDA substances FDA UNII substance identifier 0578QTK490 UNII - - - chemical {"approval_status":null,"molecular_formula":"C4H2O4.2Na","source_table":"substance_identifiers_fda","substance_class":"chemical","unii_code":"0578QTK490"}