Good Cosmetic Ingredient

Disodium Nonoxynol-10 Sulfosuccinate

INCI: DISODIUM NONOXYNOL-10 SULFOSUCCINATE

CAS Number
67999-57-9
Function
Surfactant – cleansing, foam boosting, hydrotrope
Safety Rating
GOOD

Regulatory Status

🇪🇺 EU Status permitted
🇺🇸 US Status permitted
US Notes Permitted — not prohibited under 21 CFR; CIR Panel concluded alkyl PEG sulfosuccinates safe as used when formulated to be nonirritating

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
adequate
Dermal Absorption
negligible
Sensitization
low

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

Potential for ocular and skin irritation at higher concentrations; contains ethoxylated nonoxynol chain — must monitor for 1,4-dioxane and ethylene oxide residuals

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Concern Level: Moderate

Frequently Asked Questions

Is Disodium Nonoxynol-10 Sulfosuccinate safe in cosmetics?

Potential for ocular and skin irritation at higher concentrations; contains ethoxylated nonoxynol chain — must monitor for 1,4-dioxane and ethylene oxide residuals The EU classifies Disodium Nonoxynol-10 Sulfosuccinate as "permitted". Safety rating: GOOD.

Is Disodium Nonoxynol-10 Sulfosuccinate allowed in the EU?

Disodium Nonoxynol-10 Sulfosuccinate EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Disodium Nonoxynol-10 Sulfosuccinate do in cosmetics?

Disodium Nonoxynol-10 Sulfosuccinate functions as: Surfactant – cleansing, foam boosting, hydrotrope. It is classified as a cosmetic ingredient in our database. CAS number: 67999-57-9.

What is the Margin of Safety for Disodium Nonoxynol-10 Sulfosuccinate?

adequate The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

Compliance Tools

Check Disodium Nonoxynol-10 Sulfosuccinate compliance across multiple jurisdictions:

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Ingredient Decoder
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82 Allergen Checker
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Substance Compliance
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MoS Calculator
Calculate Margin of Safety using SCCS methodology
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Heavy Metal Limits
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