Isolongifolene Epoxide

INCI: ISOLONGIFOLENE EPOXIDE

CAS Number
67999-56-8
Function
Fragrance ingredient
Safety Rating
MODERATE

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status permitted
๐Ÿ‡บ๐Ÿ‡ธ US Status permitted
US Notes Permitted โ€” no specific CFR restriction

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
not established
Dermal Absorption
low
Sensitization
moderate

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

The epoxide moiety is a structural alert for skin sensitization via hapten formation. Requires IFRA-compliant use levels. Limited ingredient-specific toxicological data; read-across from parent isolongifolene may be acceptable for CPSR but should be justified.

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Concern Level: Moderate

Regulatory Flags

potential-allergen fragrance-component

Frequently Asked Questions

Is Isolongifolene Epoxide safe in cosmetics?

The epoxide moiety is a structural alert for skin sensitization via hapten formation. Requires IFRA-compliant use levels. Limited ingredient-specific toxicological data; read-across from parent isolongifolene may be acceptable for CPSR but should be justified. The EU classifies Isolongifolene Epoxide as "permitted". Safety rating: MODERATE.

Is Isolongifolene Epoxide allowed in the EU?

Isolongifolene Epoxide EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Isolongifolene Epoxide do in cosmetics?

Isolongifolene Epoxide functions as: Fragrance ingredient. It is classified as a cosmetic ingredient in our database. CAS number: 67999-56-8.

What is the Margin of Safety for Isolongifolene Epoxide?

not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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