Regulatory Status
For full compliance data across 55 jurisdictions, use the Substance Compliance tool.
Safety Data
Calculate MoS for your specific formulation with the MoS Calculator.
Toxicological Studies
8 study endpoints found for Disodium Sebacate. NOAEL (No Observed Adverse Effect Level) values are used to calculate the Margin of Safety per SCCS methodology.
| Endpoint | Value | Route | Species | Study Type | Source |
|---|---|---|---|---|---|
| NOEL | >=1000 mg/kg bw/day | oral | rat | oral | REACH |
| NOAEL | 1 other | oral | rat | oral | REACH |
| NOEL | >=1500 mg/kg bw/day | oral | rabbit | oral | REACH |
| NOAEL | 200 other | oral | rat | oral | REACH |
| LOAEL | 400 other | oral | rat | oral | REACH |
| NOAEL | 1 other | oral | - | oral | REACH |
| NOAEL | 200 other | oral | - | oral | REACH |
| NOAEL | 400 other | oral | - | oral | REACH |
Expert Verdict
Minimal concerns. Castor oil-derived. Also used in corrosion inhibitors and industrial lubricants; ensure cosmetic-grade sourcing with certificate of analysis confirming purity and heavy metals compliance.
Frequently Asked Questions
Is Disodium Sebacate safe in cosmetics?
Minimal concerns. Castor oil-derived. Also used in corrosion inhibitors and industrial lubricants; ensure cosmetic-grade sourcing with certificate of analysis confirming purity and heavy metals compliance. The EU classifies Disodium Sebacate as "permitted". Safety rating: GOOD. 8 toxicological study endpoint(s) are available in our database.
Is Disodium Sebacate allowed in the EU?
Disodium Sebacate EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.
What does Disodium Sebacate do in cosmetics?
Disodium Sebacate functions as: Light stabilizer; protects product from photodegradation. It is classified as a cosmetic ingredient in our database. CAS number: 17265-14-4.
What is the Margin of Safety for Disodium Sebacate?
not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.
What is the NOAEL for Disodium Sebacate?
The NOAEL (No Observed Adverse Effect Level) for Disodium Sebacate is >=1000 mg/kg bw/day based on a oral study via oral route in rat. A total of 8 study endpoints are available. Source: REACH.
Compliance Tools
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Related Ingredients
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