NOAEL Studies Cosmetic Ingredient

Dodecanedioic Acid NOAEL Studies

INCI: DODECANEDIOIC ACID

CAS: 693-23-2

Raw No Observed Adverse Effect Level endpoint records grouped by source. This page does not render calculated Margin of Safety values.

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ToxValDB_ECHA_IUCLID 3 endpoints
Source Endpoint Type Value Unit Species Route Duration Study Type Reference
ToxValDB_ECHA_IUCLID NOAEL =1000 mg/kg bw/day Rat oral - developmental QUALITY=1 (reliable without restriction); STORED_SOURCE_RECORD=https://clowder.edap-cluster.com/files/669eac62e4b0a7c65d1bec8e; RECORD_SOURCE_LEVEL=Extraction document; SOURCE_URL=https://echa.europa.eu/; SUBSOURCE_URL=https://echa.europa.eu/registration-dossier/-/registered-dossier/14886/7/9/3?documentUUID=00fb5197-0aee-4d9c-bbf2-d31e3a017ae1; YEAR=0; ORIGINAL_YEAR=0; STUDY_GROUP=ECHA IUCLID:15825117:M/F:-fetal; QC_CATEGORY=Programmatically extracted from structured data source; Source overall passed QC, and this record was expert reviewed; QC_STATUS=pass; SOURCE_HASH=ToxValhc_fdeb8ad8a1f3acd0663c821028145eb0
ToxValDB_ECHA_IUCLID NOAEL =1800 mg/kg bw/day Rat oral subchronic; 13 weeks subchronic QUALITY=1 (reliable without restriction); STORED_SOURCE_RECORD=https://clowder.edap-cluster.com/files/669eaec9e4b0a7c65d1cb043; RECORD_SOURCE_LEVEL=Extraction document; SOURCE_URL=https://echa.europa.eu/; SUBSOURCE_URL=https://echa.europa.eu/registration-dossier/-/registered-dossier/14886/7/6/2?documentUUID=00fb5197-0aee-4d9c-bbf2-d31e3a017ae1; YEAR=0; ORIGINAL_YEAR=0; STUDY_GROUP=ECHA IUCLID_dup_Repeated Dose Toxicity Oral_15849505_15849506:M/F:--; QC_CATEGORY=Programmatically extracted from structured data source; Source overall passed QC, and this record was expert reviewed; QC_STATUS=pass; SOURCE_HASH=ToxValhc_74c938b8d74d55869ffe60c3231b0d21
ToxValDB_ECHA_IUCLID NOAEL =2400 mg/kg bw/day Rat oral short-term; 14 days short-term QUALITY=1 (reliable without restriction); STORED_SOURCE_RECORD=https://clowder.edap-cluster.com/files/66a7cba9e4b0a7c65d227056; RECORD_SOURCE_LEVEL=Extraction document; SOURCE_URL=https://echa.europa.eu/; SUBSOURCE_URL=https://echa.europa.eu/registration-dossier/-/registered-dossier/14886/7/6/2?documentUUID=00fb5197-0aee-4d9c-bbf2-d31e3a017ae1; YEAR=0; ORIGINAL_YEAR=0; STUDY_GROUP=ECHA IUCLID_dup_Repeated Dose Toxicity Oral_15849507_15849508:M/F:--; QC_CATEGORY=Programmatically extracted from structured data source; Source overall passed QC, and this record was expert reviewed; QC_STATUS=pass; SOURCE_HASH=ToxValhc_1b54bb57879f0ff650cb24751df536f3
ToxValDB_GESTIS_DNEL 1 endpoint
Source Endpoint Type Value Unit Species Route Duration Study Type Reference
ToxValDB_GESTIS_DNEL DNEL systemic =127 mg/m3 Human inhalation - Toxicity Value STORED_SOURCE_RECORD=https://clowder.edap-cluster.com/files/6543dd69e4b045b9ff7cd87e; RECORD_SOURCE_LEVEL=Extraction document; SOURCE_URL=https://www.dguv.de/ifa/gestis/gestis-dnel-liste/index-2.jsp; STUDY_GROUP=GESTIS DNEL:15631786:-:--; QC_CATEGORY=Programmatically extracted from structured data source; Source overall passed QC, but this record was not manually checked; QC_STATUS=not determined; SOURCE_HASH=ToxValhc_2d32d55fc9604e5311984d0bb4a99f0c
openFDA substances 4 endpoints
Source Endpoint Type Value Unit Species Route Duration Study Type Reference
openFDA substances FDA UNII substance identifier 978YU42Q6I UNII - - - chemical {"approval_status":null,"molecular_formula":"C12H22O4","source_table":"substance_identifiers_fda","substance_class":"chemical","unii_code":"978YU42Q6I"}
openFDA substances FDA UNII substance identifier 978YU42Q6I UNII - - - chemical {"approval_status":null,"molecular_formula":"C12H22O4","source_table":"substance_identifiers_fda","substance_class":"chemical","unii_code":"978YU42Q6I"}
openFDA substances FDA UNII substance identifier 978YU42Q6I UNII - - - chemical {"approval_status":null,"molecular_formula":"C12H22O4","source_table":"substance_identifiers_fda","substance_class":"chemical","unii_code":"978YU42Q6I"}
openFDA substances FDA UNII substance identifier 978YU42Q6I UNII - - - chemical {"approval_status":null,"molecular_formula":"C12H22O4","source_table":"substance_identifiers_fda","substance_class":"chemical","unii_code":"978YU42Q6I"}