Dodecyl Gallate

INCI: DODECYL GALLATE

CAS Number
1166-52-5
Function
Antioxidant
Safety Rating
GOOD

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status permitted
๐Ÿ‡บ๐Ÿ‡ธ US Status permitted
US Notes Permitted as GRAS food-grade antioxidant; no 21 CFR cosmetic restriction

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
adequate
Dermal Absorption
low
Sensitization
moderate

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

Phenolic antioxidant with reports of allergic contact dermatitis; cross-reactivity with propyl and octyl gallate possible; removed from EU food use under Regulation (EU) 2018/1481 as a risk-management decision rather than direct toxicological ban.

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Concern Level: Moderate

Regulatory Flags

fda_food_additive jecfa_concern

Frequently Asked Questions

Is Dodecyl Gallate safe in cosmetics?

Phenolic antioxidant with reports of allergic contact dermatitis; cross-reactivity with propyl and octyl gallate possible; removed from EU food use under Regulation (EU) 2018/1481 as a risk-management decision rather than direct toxicological ban. The EU classifies Dodecyl Gallate as "permitted". Safety rating: GOOD.

Is Dodecyl Gallate allowed in the EU?

Dodecyl Gallate EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Dodecyl Gallate do in cosmetics?

Dodecyl Gallate functions as: Antioxidant. It is classified as a cosmetic ingredient in our database. CAS number: 1166-52-5.

What is the Margin of Safety for Dodecyl Gallate?

adequate The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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