Is Dodecylhexadecyltrimonium Chloride safe in cosmetics?
Dodecylhexadecyltrimonium Chloride has a safety rating of "MODERATE" in our database. EU status: restricted. US status: permitted.
MODERATE
Cosmetic Ingredient
Dodecylhexadecyltrimonium Chloride
INCI: DODECYLHEXADECYLTRIMONIUM CHLORIDE
Dodecylhexadecyltrimonium Chloride (CAS 103807-18-7) is a cosmetic cosmetic ingredient functioning as Antistatic, hair conditioning, surfactant-cleansing, surfactant-emulsifying. EU Regulation 1223/2009 status: restricted. Industrial safety data is also available in the chemical safety database.
View industrial chemical safety profile for CAS 103807-18-7 →
Function
Antistatic, hair conditioning, surfactant-cleansing, surfactant-emulsifying
Editorial assessment
MODERATE
Preliminary editorial note — not a computed safety verdict.
Chemistry & Identifiers
IUPAC Name
2-dodecylhexadecyl(trimethyl)azanium chloride
InChIKey
CYZIPMMNONORGD-UHFFFAOYSA-M
Regulatory Status
EU EU Status
restricted
US US Status
permitted
US Notes
Permitted — not individually restricted under 21 CFR; CIR reviewed trimoniums as safe with concentration caveats
For full compliance data across multiple jurisdictions, use the Substance Compliance tool.
Safety Data
Margin of Safety, dermal absorption, and sensitization profile summaries for Dodecylhexadecyltrimonium Chloride.
Calculate MoS for your specific formulation with the MoS Calculator.
Function Categories & List Membership
Cosmetic/Chemical Function Categories
Anti-static agent
Emulsifier
Softener and conditioner
Surfactant (surface active agent)
Editorial summary
Preliminary editorial summary for Dodecylhexadecyltrimonium Chloride — not a computed safety verdict. See the sourced toxicological data above.
Regulatory Flags
potential-allergen
Chemical Function
Surfactant (surface active agent)
Anti-static agent
Emulsifier
Softener and conditioner
Frequently Asked Questions
Is Dodecylhexadecyltrimonium Chloride allowed in the EU?
Dodecylhexadecyltrimonium Chloride EU regulatory status: restricted. This is based on EU Regulation 1223/2009 and its amendments.
What does Dodecylhexadecyltrimonium Chloride do in cosmetics?
Dodecylhexadecyltrimonium Chloride functions as: Antistatic, hair conditioning, surfactant-cleansing, surfactant-emulsifying. It is classified as a cosmetic ingredient in our database. CAS number: 103807-18-7.
Compliance Tools
Check Dodecylhexadecyltrimonium Chloride compliance across multiple jurisdictions:
Ingredient Decoder
Paste a full ingredient list for instant analysis
82 Allergen Checker
Check for EU declarable fragrance allergens
Substance Compliance
Check compliance across multiple jurisdictions
MoS Calculator
Calculate Margin of Safety using SCCS methodology
Heavy Metal Limits
Compare limits across jurisdictions
Related Ingredients
Alpha-Glucan Oligosaccharide-1
EXCELLENT
Same category
Skin conditioning, cleansing, smoothi...
Ammonium Acryloyl Dimethyltaurate/Carboxyethyl Acrylate Crosspolymer
EXCELLENT
Same category
Dispersing agent (nonsurfactant), vis...
Ammonium Cocoyl Isethionate
EXCELLENT
Same category
Surfactant – cleansing, foaming
Ammonium Lauryl Sulfosuccinate
EXCELLENT
Same category
Cleansing, foaming, surfactant
Ammonium Stearate
EXCELLENT
Same category
Cleansing, surfactant, emulsifying
Apricot Kernel Oil Polyglyceryl-10 Esters
EXCELLENT
Same category
Skin conditioning, emollient, surfact...
(20S)-Protopanaxadiol
MODERATE
Similar safety
(Cnidium Officinale/Coptis Chinensis/Glycyrrhiza Uralensis) Root Extract
MODERATE
Similar safety
Skin conditioning
(Cryptomeria Japonica/Chamaecyparis Obtusa) Stem Ferment Extract
MODERATE
Similar safety
Antimicrobial, antioxidant, humectant
(Eclipta Prostrata/Houttuynia Cordata) Leaf Extract
MODERATE
Similar safety
Skin conditioning
(Lepidium Meyenii/Sarcodon Aspratus) Root Water
MODERATE
Similar safety
Skin conditioning
(Licorice/Reynoutria Japonica) Root/Stem Extract
MODERATE
Similar safety
Skin conditioning, antioxidant
DODECAHYDRO-TETRAMETHYLNAPHTHOFURAN
GOOD
Browse nearby
Perfuming
DUNALIELLA SALINA/ISOCHRYSIS GALBANA/NANNOCHLOROPSIS GADITANA/PHAEODACTYLUM TRICORNUTUM/TETRASELMIS CHUII EXTRACT
GOOD
Browse nearby
Antioxidant, Skin Conditioning
DVB/Isobornyl Methacrylate/Lauryl Methacrylate Copolymer
GOOD
Browse nearby
Absorbent (oil/sebum absorber; mattif...
Is Dodecylhexadecyltrimonium Chloride in Your Products?
Scan any product label with Piro — our free ingredient scanner. Point your camera at the ingredients list and get instant safety scores for every ingredient.
Try Piro Free →Analyze Your Full Ingredient List
Paste any INCI list into the Decoder for instant safety analysis, or calculate the Margin of Safety for Dodecylhexadecyltrimonium Chloride in your formulation.