Moderate Cosmetic Ingredient NOAEL Data

Eclipta Prostrata Extract

INCI: ECLIPTA PROSTRATA EXTRACT

CAS Number
93165-22-1
Function
Skin Conditioning, Antioxidant, Hair Conditioning
Safety Rating
MODERATE

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status permitted
๐Ÿ‡บ๐Ÿ‡ธ US Status permitted
US Notes No specific FDA restrictions under 21 CFR; no CIR safety assessment published; must be declared under MoCRA product listing

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
not established
Dermal Absorption
moderate
Sensitization
moderate

Calculate MoS for your specific formulation with the MoS Calculator.

Toxicological Studies

1 study endpoint found for Eclipta Prostrata Extract. NOAEL (No Observed Adverse Effect Level) values are used to calculate the Margin of Safety per SCCS methodology.

Endpoint Value Route Species Study Type Source
NOAEL 1000 mg/kg bw/day oral rat oral REACH

Expert Verdict

Multifunctional botanical with antioxidant and hair conditioning benefits, but lacking SCCS opinion, CIR safety assessment, dermal absorption data, and sensitization studies; potential contact dermatitis risk in individuals with Asteraceae allergies due to sesquiterpene lactone cross-reactivity.

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Concern Level: Moderate

Regulatory Flags

plant-extract asteraceae-family sensitization-risk compositae-allergen ayurvedic hair-growth antioxidant anti-inflammatory uvb-protective no-cir-report no-sccs-opinion no-dermal-absorption-data bhringraj high-documentation-burden

Frequently Asked Questions

Is Eclipta Prostrata Extract safe in cosmetics?

Multifunctional botanical with antioxidant and hair conditioning benefits, but lacking SCCS opinion, CIR safety assessment, dermal absorption data, and sensitization studies; potential contact dermatitis risk in individuals with Asteraceae allergies due to sesquiterpene lactone cross-reactivity. The EU classifies Eclipta Prostrata Extract as "permitted". Safety rating: MODERATE. 1 toxicological study endpoint(s) are available in our database.

Is Eclipta Prostrata Extract allowed in the EU?

Eclipta Prostrata Extract EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Eclipta Prostrata Extract do in cosmetics?

Eclipta Prostrata Extract functions as: Skin Conditioning, Antioxidant, Hair Conditioning. It is classified as a cosmetic ingredient in our database. CAS number: 93165-22-1.

What is the Margin of Safety for Eclipta Prostrata Extract?

not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

What is the NOAEL for Eclipta Prostrata Extract?

The NOAEL (No Observed Adverse Effect Level) for Eclipta Prostrata Extract is 1000 mg/kg bw/day based on a oral study via oral route in rat. Source: REACH.

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