NOAEL Studies UV Filter / Sunscreen

Enzacamene (4-Methylbenzylidene Camphor) NOAEL Studies

INCI: ENZACAMENE

CAS: 36861-47-9

Raw No Observed Adverse Effect Level endpoint records grouped by source. This page does not render calculated Margin of Safety values.

Back to parent ingredient page
SCCS Opinion 22 endpoints
Source Endpoint Type Value Unit Species Route Duration Study Type Reference
SCCS Opinion NOAEL =1 - - oral - NOAEL study p.10
SCCS Opinion NOAEL =4 - - - - NOAEL study p.32
SCCS Opinion NOAEL =10 mg/kg bw/day - - Developmental developmental toxicity p.25
SCCS Opinion NOAEL =25 - rat oral - NOAEL study p.3
SCCS Opinion NOAEL =25 mg/kg/day rat oral 90-day genotoxicity p.7
SCCS Opinion NOAEL =25 mg/kg bw/day - dermal subchronic repeated dose toxicity p.8
SCCS Opinion NOAEL =25 mg/kg rat dermal - NOAEL study p.10
SCCS Opinion NOAEL =25 mg/kg bw/day rat oral Sub-chronic repeated dose toxicity p.21
SCCS Opinion NOAEL =30 mg/kg bw/day rat oral 17-day NOAEL study p.6
SCCS Opinion NOAEL =30 mg/kg bw/day rat - developmental developmental toxicity Ref.: Gleich et al, p.25
SCCS Opinion NOAEL =50 mg/kg/day rat - - reproductive toxicity p.22
SCCS Opinion NOAEL =50 mg/kg bw/day - oral 90-day reproductive toxicity p.38
SCCS Opinion NOAEL =66 mg/kg bw/day human dermal - NOAEL study p.32
SCCS Opinion NOAEL =100 mg/kg bw/day - - developmental developmental toxicity p.9
SCCS Opinion NOAEL =100 mg/kg/day rat dermal 90 day NOAEL study p.24
SCCS Opinion NOAEL =100 mg/kg/day rat dermal 90-day repeated dose toxicity p.18
SCCS Opinion NOAEL =100 mg/kg bw/day rat dermal 90d reproductive toxicity p.21
SCCS Opinion NOAEL =400 - rat oral - NOAEL study p.22
SCCS Opinion NOAEL =400 mg/kg/day rat dermal 90 day NOAEL study p.24
SCCS Opinion NOAEL =400 mg/kg bw/day rat oral 90d reproductive toxicity p.21
SCCS Opinion NOAEL =400 mg/kg bw /day - oral 90-day NOAEL study p.24
SCCS Opinion NOAEL =2000 mg/kg bw/day rat - chronic NOAEL study p.24
Regulatory source 39 endpoints
Source Endpoint Type Value Unit Species Route Duration Study Type Reference
Regulatory source - 1 - - oral - - p.10
Regulatory source - 4 - - - - - p.32
Regulatory source - 25 - rat oral - - p.3
Regulatory source - 25 mg/kg rat dermal - - p.10
Regulatory source - 25 mg/kg bw/day - - - - p.24
Regulatory source - 25 mg/kg bw/day - oral 90-day - p.24
Regulatory source - =30 mg/kg bw/day rat oral 17-day - p.6
Regulatory source - 66 mg/kg bw/day human dermal - - p.32
Regulatory source - 100 mg/kg/day rat dermal 90 day - p.24
Regulatory source - 100 mg/kg/day rat dermal 90-day - p.18
Regulatory source - 100 mg/kg bw/day - oral 90-day - p.41
Regulatory source - =400 - rat oral - - p.22
Regulatory source - 400 mg/kg/day rat dermal 90 day - p.24
Regulatory source - 400 mg/kg bw /day - oral 90-day - p.24
Regulatory source - 2000 mg/kg bw/day rat - chronic - p.24
Regulatory source developmental toxicity 10 mg/kg bw/day - - Developmental developmental toxicity p.25
Regulatory source developmental toxicity 10 mg/kg bw/day rat - Developmental developmental toxicity p.25
Regulatory source developmental toxicity 10 mg/kg bw/day rat oral developmental developmental toxicity p.25
Regulatory source developmental toxicity 25 mg/kg bw/day - - developmental developmental toxicity p.25
Regulatory source developmental toxicity 30 mg/kg bw/day rat - developmental developmental toxicity p.25
Regulatory source developmental toxicity 30 mg/kg bw/day - - 90-day developmental toxicity p.40
Regulatory source developmental toxicity 100 mg/kg bw/day - - developmental developmental toxicity p.9
Regulatory source developmental toxicity 100 mg/kg/day rat oral developmental developmental toxicity p.25
Regulatory source developmental toxicity 400 mg/kg bw/day - oral 90-day developmental toxicity p.40
Regulatory source genotoxicity =25 mg/kg/day rat oral 90-day genotoxicity p.7
Regulatory source repeated dose toxicity 25 mg/kg bw/day - dermal subchronic repeated dose toxicity p.8
Regulatory source repeated dose toxicity 25 mg/kg bw/day rat oral Sub-chronic repeated dose toxicity p.21
Regulatory source repeated dose toxicity 25 mg/kg bw/day rat oral 28-day repeated dose toxicity p.39
Regulatory source repeated dose toxicity 100 mg/kg/day rat dermal 90-day repeated dose toxicity p.18
Regulatory source reproductive toxicity 25 mg/kg bw/day rat - - reproductive toxicity p.24
Regulatory source reproductive toxicity 25 mg/kg bw/day - oral 90-day reproductive toxicity p.38
Regulatory source reproductive toxicity 25 mg/kg bw/day - dermal - reproductive toxicity p.40
Regulatory source reproductive toxicity 25 mg/kg bw/day - - - reproductive toxicity p.40
Regulatory source reproductive toxicity 50 mg/kg/day rat - - reproductive toxicity p.22
Regulatory source reproductive toxicity 50 mg/kg bw/day - oral 90-day reproductive toxicity p.38
Regulatory source reproductive toxicity 100 mg/kg bw/day rat dermal 90d reproductive toxicity p.21
Regulatory source reproductive toxicity 100 mg/kg bw/day - oral - reproductive toxicity p.38
Regulatory source reproductive toxicity 100 mg/kg bw/day - dermal - reproductive toxicity p.40
Regulatory source reproductive toxicity 400 mg/kg bw/day rat oral 90d reproductive toxicity p.21
openFDA substances 1 endpoint
Source Endpoint Type Value Unit Species Route Duration Study Type Reference
openFDA substances FDA UNII substance identifier 8I3XWY40L9 UNII - - - chemical -