Ethiodized Oil

INCI: ETHIODIZED OIL

CAS Number
8008-53-5 [^1_10]
Function
Radiographic contrast medium (pharmaceutical); limited cosmetic relevance — sometimes listed as skin-conditioning agent
Safety Rating
MODERATE

Regulatory Status

🇪🇺 EU Status permitted
🇺🇸 US Status permitted
US Notes Permitted — no specific CFR prohibition; however, it is an FDA-regulated injectable drug (Lipiodol); cosmetic use would require full safety substantiation

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
adequate
Dermal Absorption
negligible
Sensitization
low

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

Iodine content may cause reactions in iodine-sensitive individuals; moderately toxic by parenteral routes; primarily a pharmaceutical — cosmetic use would require full toxicological dossier from a qualified Safety Assessor; no established cosmetic use history

⚠️
Concern Level: High

Regulatory Flags

plant-oil

Frequently Asked Questions

Is Ethiodized Oil safe in cosmetics?

Iodine content may cause reactions in iodine-sensitive individuals; moderately toxic by parenteral routes; primarily a pharmaceutical — cosmetic use would require full toxicological dossier from a qualified Safety Assessor; no established cosmetic use history The EU classifies Ethiodized Oil as "permitted". Safety rating: MODERATE.

Is Ethiodized Oil allowed in the EU?

Ethiodized Oil EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Ethiodized Oil do in cosmetics?

Ethiodized Oil functions as: Radiographic contrast medium (pharmaceutical); limited cosmetic relevance — sometimes listed as skin-conditioning agent. It is classified as a cosmetic ingredient in our database. CAS number: 8008-53-5 [^1_10].

What is the Margin of Safety for Ethiodized Oil?

adequate The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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