Is Ethyl Menthane Carboxamide safe in cosmetics?
Ethyl Menthane Carboxamide has a safety rating of "GOOD" in our database. EU status: permitted. US status: permitted.
Good
Cosmetic Ingredient
Ethyl Menthane Carboxamide
Also known as: N-Ethyl-p-menthane-3-carboxamide, Cyclohexanecarboxamide, N-ethyl-5-methyl-2-(1-methylethyl)-, N-Ethyl-4-menthane-3-carboxamide, EINECS 254-599-0, N-Ethyl-2-isopropyl-5-methylcyclohexane carboxamide (+2 more)
INCI: ETHYL MENTHANE CARBOXAMIDE
Ethyl Menthane Carboxamide (CAS 39711-79-0) is a cosmetic cosmetic ingredient functioning as Cooling agent providing menthol-type sensorial effect without menthol odor. NOAEL 8 mg/kg bw/day (cross-referenced against ToxValDB ECHA IUCLID); EU Regulation 1223/2009 status: permitted. Industrial safety data is also available in the chemical safety database. Same-CAS public records also appear in industrial chemical safety and pharmaceutical data.
View industrial chemical safety profile for CAS 39711-79-0 →
Auto-generated CPSR Part A draft with source citations
Function
Cooling agent providing menthol-type sensorial effect without menthol odor
Safety Rating
GOOD
Chemistry & Identifiers
IUPAC Name
N-ethyl-5-methyl-2-propan-2-ylcyclohexane-1-carboxamide
InChIKey
VUNOFAIHSALQQH-UHFFFAOYSA-N
Regulatory Status
EU EU Status
permitted
US US Status
permitted
US Notes
Permitted with no specific CFR restriction
For full compliance data across multiple jurisdictions, use the Substance Compliance tool.
Safety Data
Margin of Safety, dermal absorption, and sensitization profile summaries for Ethyl Menthane Carboxamide.
Calculate MoS for your specific formulation with the MoS Calculator.
Pre-Calculated Safety Assessment
Pre-calculated NOAEL → SED → MoS audit trail for Ethyl Menthane Carboxamide across SCCS product categories, with measured dermal absorption where available.
ECHA REACH Registration
European Chemicals Agency REACH dossier and Substances of Very High Concern listing.
Registration Type
Full
Tonnage Band
100 - 1,000 tonnes
Substance Type
SUBSTANCE
SVHC Candidate
No
PubChem Annotations
Safety and regulatory annotations from PubChem (NCBI) aggregated sources.
Regulatory (2)
JECFA Number
1601
Source: Joint FAO/WHO Expert Committee on Food Additives (JECFA)
JECFA Evaluation
N-ETHYL 2-ISOPROPYL-5-METHYLCYCLOHEXANECARBOXAMIDE | 2005 | No safety concern at current levels of intake when used as a flavouring agent | TRS 934-JECFA 65/89 | FAS 56-JECFA 65
Source: Joint FAO/WHO Expert Committee on Food Additives (JECFA)
Function Categories & List Membership
Cosmetic/Chemical Function Categories
Flavouring and nutrient
Fragrance
Humectant
Regulatory List Membership (2)
IFRA Fragrance Transparency List
FDA Substances Added to Food (EAFUS)
Expert Verdict
Expert safety assessment and concern-level summary for Ethyl Menthane Carboxamide.
Regulatory Flags
ifra_fragrance
fda_food_additive
Known Synonyms
N-Ethyl-p-menthane-3-carboxamide
Cyclohexanecarboxamide, N-ethyl-5-methyl-2-(1-methylethyl)-
N-Ethyl-4-menthane-3-carboxamide
EINECS 254-599-0
N-Ethyl-2-isopropyl-5-methylcyclohexane carboxamide
FEMA No. 3455
UNII-6S7S02945H
Chemical Function
Humectant
Flavouring and nutrient
Fragrance
Regulatory Lists
IFRA Transparency
Europe
food_additive; Substances Added to Food (formerly EAFUS) (2/2019)
Australian Status
AICIS status: listed
Cross-Vertical Safety Context
Same-CAS public records found in pharmaceutical data.
SOURCE
ChEMBL / DrugCentral / FAERS
DB_PHARMA CAS match
Pharmaceutical Data
Same-CAS rows from the pharmaceutical spoke database.
ChEMBL ID
CHEMBL3185043
Frequently Asked Questions
Is Ethyl Menthane Carboxamide allowed in the EU?
Ethyl Menthane Carboxamide EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.
What does Ethyl Menthane Carboxamide do in cosmetics?
Ethyl Menthane Carboxamide functions as: Cooling agent providing menthol-type sensorial effect without menthol odor. It is classified as a cosmetic ingredient in our database. CAS number: 39711-79-0.
Is Ethyl Menthane Carboxamide used outside cosmetics?
Ethyl Menthane Carboxamide also appears in industrial chemical safety and pharmaceutical data. The cross-vertical cards on this page render same-CAS public rows from the matched databases.
Compliance Tools
Check Ethyl Menthane Carboxamide compliance across multiple jurisdictions:
Ingredient Decoder
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82 Allergen Checker
Check for EU declarable fragrance allergens
Substance Compliance
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MoS Calculator
Calculate Margin of Safety using SCCS methodology
Heavy Metal Limits
Compare limits across jurisdictions
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