Regulatory Status
For full compliance data across 55 jurisdictions, use the Substance Compliance tool.
Safety Data
Calculate MoS for your specific formulation with the MoS Calculator.
Toxicological Studies
6 study endpoints found for Ethyl Menthane Carboxamide. NOAEL (No Observed Adverse Effect Level) values are used to calculate the Margin of Safety per SCCS methodology.
| Endpoint | Value | Route | Species | Study Type | Source |
|---|---|---|---|---|---|
| NOAEL | 300 mg/kg bw/day | oral | rat | Subchronic | COSMOS_DB |
| NOAEL | 1000 mg/kg bw/day | oral | dog | Chronic | COSMOS_DB |
| NOAEL | 300 other | oral | rat | oral | REACH |
| LOAEL | 600 other | oral | dog | oral | REACH |
| LOAEL | 100 other | oral | dog | oral | REACH |
| NOEL | 8 other | oral | rat | oral | REACH |
Expert Verdict
Patch test recommended for hypersensitive individuals; suitable for all skin types; vegan and halal
Regulatory Flags
Frequently Asked Questions
Is Ethyl Menthane Carboxamide safe in cosmetics?
Patch test recommended for hypersensitive individuals; suitable for all skin types; vegan and halal The EU classifies Ethyl Menthane Carboxamide as "permitted". Safety rating: GOOD. 6 toxicological study endpoint(s) are available in our database.
Is Ethyl Menthane Carboxamide allowed in the EU?
Ethyl Menthane Carboxamide EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.
What does Ethyl Menthane Carboxamide do in cosmetics?
Ethyl Menthane Carboxamide functions as: Cooling agent providing menthol-type sensorial effect without menthol odor. It is classified as a cosmetic ingredient in our database. CAS number: 39711-79-0.
What is the Margin of Safety for Ethyl Menthane Carboxamide?
adequate The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.
What is the NOAEL for Ethyl Menthane Carboxamide?
The NOAEL (No Observed Adverse Effect Level) for Ethyl Menthane Carboxamide is 300 mg/kg bw/day based on a Subchronic study via oral route in rat. A total of 6 study endpoints are available. Source: COSMOS_DB.
Compliance Tools
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Related Ingredients
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