Ethyl Serinate

INCI: ETHYL SERINATE

CAS Number
4117-31-1 (L-form, hydrochloride: 26348-61-8)
Function
Skin/hair conditioning agent (amino acid ester)
Safety Rating
MODERATE

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status permitted
๐Ÿ‡บ๐Ÿ‡ธ US Status permitted
US Notes Permitted โ€” no specific CFR restriction

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
not established
Dermal Absorption
moderate
Sensitization
low

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

Insufficient toxicological data for CPSR. Amino acid ester class read-across may support preliminary assessment, but formal genotoxicity, sensitization, and repeated dose studies are needed before inclusion in a finished product safety report.

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Concern Level: Moderate

Regulatory Flags

potential-allergen

Frequently Asked Questions

Is Ethyl Serinate safe in cosmetics?

Insufficient toxicological data for CPSR. Amino acid ester class read-across may support preliminary assessment, but formal genotoxicity, sensitization, and repeated dose studies are needed before inclusion in a finished product safety report. The EU classifies Ethyl Serinate as "permitted". Safety rating: MODERATE.

Is Ethyl Serinate allowed in the EU?

Ethyl Serinate EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Ethyl Serinate do in cosmetics?

Ethyl Serinate functions as: Skin/hair conditioning agent (amino acid ester). It is classified as a cosmetic ingredient in our database. CAS number: 4117-31-1 (L-form, hydrochloride: 26348-61-8).

What is the Margin of Safety for Ethyl Serinate?

not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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