Ethyl Trimethylbenzoyl Phenylphosphinate (TPO-L)

INCI: ETHYL TRIMETHYLBENZOYL PHENYLPHOSPHINATE

CAS Number
84434-11-7
Function
UV Absorber / Photoinitiator (primarily nail gel systems)
Safety Rating
MODERATE

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status permitted
๐Ÿ‡บ๐Ÿ‡ธ US Status permitted
US Notes Permitted โ€” no specific CFR restriction for cosmetic use

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
not established
Dermal Absorption
moderate
Sensitization
moderate

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

Photoinitiator class under increasing EU regulatory scrutiny; generates free radicals under UV exposure by design. Contact sensitization reports exist for the broader acylphosphinate class. Use should be restricted to UV-cured nail systems; not appropriate for leave-on skin products.

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Concern Level: Moderate

Regulatory Flags

potential-allergen

Frequently Asked Questions

Is Ethyl Trimethylbenzoyl Phenylphosphinate (TPO-L) safe in cosmetics?

Photoinitiator class under increasing EU regulatory scrutiny; generates free radicals under UV exposure by design. Contact sensitization reports exist for the broader acylphosphinate class. Use should be restricted to UV-cured nail systems; not appropriate for leave-on skin products. The EU classifies Ethyl Trimethylbenzoyl Phenylphosphinate (TPO-L) as "permitted". Safety rating: MODERATE.

Is Ethyl Trimethylbenzoyl Phenylphosphinate (TPO-L) allowed in the EU?

Ethyl Trimethylbenzoyl Phenylphosphinate (TPO-L) EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Ethyl Trimethylbenzoyl Phenylphosphinate (TPO-L) do in cosmetics?

Ethyl Trimethylbenzoyl Phenylphosphinate (TPO-L) functions as: UV Absorber / Photoinitiator (primarily nail gel systems). It is classified as a cosmetic ingredient in our database. CAS number: 84434-11-7.

What is the Margin of Safety for Ethyl Trimethylbenzoyl Phenylphosphinate (TPO-L)?

not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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